Kay Ohlendieck

Prof Kay Ohlendieck

Biology, Human Health Institute

Professor

Location Callan

Room 2.33

Phone (01) 708 3842

Email kay.ohlendieck@mu.ie

Biography
Publications

Biography

Education: 1980-1985 Diplom in Biology (M.Sc.), University of Konstanz, Germany; 1985-1989 Ph.D. in Biochemistry, University College Cork; Positions: 1989-1991 Postdoctoral fellow, University of Iowa, Iowa City; 1992-1994, State University of New York, Stony Brook; 1994-2002, College Lecturer, University College Dublin; 2002, Senior Lecturer in Pharmacology, University College Dublin; Since 2002: Professor and Chair, Department of Biology, National University of Ireland, Maynooth. 2011: D.Sc. for published work (NUI).

Publications

Book Chapter

	Year	Publication
	2013	Carberry S, Ohlendieck K. (2013) 'Gel electrophoresis-based proteomics of senescent tissues' In: Methods in Molecular Biology, Vol. 1048.
	2012	Lewis C, Doran P, Ohlendieck K. (2012) 'Proteomic analysis of dystrophic muscle' In: Methods in Molecular Biology, Vol. 798.
	2010	Donoghue, P., Doran, P. and Ohlendieck, K. (2010) 'Role of chaperones in dystrophic and senescent muscle fibres' In: Haugen, S. and Meijer, S(Eds.). Handbook of Nutritional Biochemistry. New York : Nova Science Publisher.
	2010	Donoghue, P., Doran, P. and Ohlendieck, K. (2010) 'Biochemical and proteomic profiling of key metabolic enzymes in aging skeletal muscle' In: Handbook of Nutritional Biochemistry. New York : Nova Science Publishers.
	2009	Ohlendieck, K. (2009) 'Centrifugation (revised)' In: Wilson, K. and Walker, J(Eds.). Principles and Techniques of Biochemistry and Molecular Biology. Cambridge, UK : Cambridge University Press.
	2005	Ohlendieck, K. (2005) 'Centrifugation' In: K. Wilson and J. Walker(Eds.). Principles and Techniques of Biochemistry and Molecular Biology. Cambridge : Cambridge University Press.
	2004	Ohlendieck, K. (2004) 'Extraction of membrane proteins' In: J.M. Walker(Eds.). Methods in Molecular Biology, Vol. 244. : Springer.
	2004	Ohlendieck, K. (2004) 'Purification of membrane proteins' In: J.M. Walker(Eds.). Methods in Molecular Biology, Vol. 244. : Springer.
	2004	Ohlendieck, K. (2004) 'Removal of detergent from protein fractions' In: J.M. Walker(Eds.). Methods in Molecular Biology, Vol. 244. : Springer.

Peer Reviewed Journal

	Year	Publication
	2013	Carberry, S., Zweyer, M., Swandulla, D., Ohlendieck, K. (2013) 'Application of Fluorescence Two-Dimensional Difference In-Gel Electrophoresis as a Proteomic Biomarker Discovery Tool in Muscular Dystrophy Research'. Journal of Biology, 2 :1438-1464. [Full-Text]
	2010	Donoghue P, Staunton L, Mullen E, Manning G, Ohlendieck K. (2010) 'DIGE analysis of rat skeletal muscle proteins using nonionic detergent phase extraction of young adult versus aged gastrocnemius tissue'. Proteomics, 73 :1441-1453. [Full-Text]
	2010	Lewis C, Jockusch H, Ohlendieck K. (2010) 'Proteomic Profiling of the Dystrophin-Deficient MDX Heart Reveals Drastically Altered Levels of Key Metabolic and Contractile Protein'. Journal of Biomedicine and Biotechnology, 2010 . [Full-Text]
	2007	Doran, P., P. Donoghue, K. O'Connell, J. Gannon and K. Ohlendieck. (2007) 'Proteomic profiling of pathological and aged skeletal muscle fibres by peptide mass fingerprinting'. International Journal of Molecular Medicine, 19 :547-564. [Full-Text]
	2007	Doran, P., J. Gannon, K. O’Connell and K. Ohlendieck. (2007) 'Aging skeletal muscle shows a drastic increase in the small heat shock proteins alphaB-crystallin/HspB5 and cvHsp/HspB7'. European Journal of Cell Biology, 86 :629-640. [Full-Text]
	2007	Schreiber, D. and K. Ohlendieck. (2007) 'Oligomerisation of sarcoplasmic reticulum Calcium-ATPase monomers from skeletal muscle'. Protein and Peptide Letters, 14 :219-226. [Full-Text]
	2007	Doran, P., J. Gannon, K. O’Connell and K. Ohlendieck. (2007) 'Proteomic profiling of animal models mimicking skeletal muscle disorders'. Proteomics - Clinical Applications, 1 :1169-1184. [Full-Text]
	2005	Donoghue, P., P. Doran, P. Dowling and K. Ohlendieck. (2005) 'Differential expression of the fast skeletal muscle proteome following chronic low-frequency stimulation. '. Biochimica et Biophysica Acta - Proteins and Proteomics, 1752 :166-176. [Full-Text]
	2005	Mulvey, C., Harno, E., Keenan, A. and Ohlendieck, K. (2005) 'Expression of the skeletal muscle dystrophin-dystroglycan complex and syntrophin-nitric oxide synthase complex is severely affected in the type 2 diabetic Goto–Kakizaki rat'. European Journal of Cell Biology, 84 :867-883. [Full-Text]
	2004	Dowling, P., Doran, P. and Ohlendieck, K. Biochem J. 379, 479-488 (2004). (2004) 'Drastic reduction of sarcalumenin in Dp427-deficient fibres indicates that abnormal calcium handling plays a key role in muscular dystrophy'. Biochemical Journal, 379 :479-488. [Full-Text]
	2004	Glover, L., Heffron, J.J.A., and Ohlendieck, K. (2004) 'Increased sensitivity of the ryanodine receptor to halothane-induced oligomerisation in malignant hyperthermia-susceptible human skeletal muscle'. Journal of Applied Physiology, 96 :11-18. [Full-Text]
	2004	Glover, L. and Ohlendieck, K. (2004) 'Illustration of skeletal muscle calsequestrin complex formation by cell overlay and two-dimensional blot overlay methodology'. BASIC AND APPLIED MYOLOGY, 14 :231-241. [Full-Text]
	2004	Doran, P., Dowling, P., Lohan, J., McDonnell, K. Poetsch, S., and Ohlendieck, K. (2004) 'Subproteomics analysis of calcium-binding proteins demonstrates decreased calsequestrin expression in dystrophic mouse skeletal muscle'. European Journal of Biochemistry, 271 :3943-3952. [Full-Text]
	2004	Donoghue, P., Ribaric, S., Moran, V., Cebasek, B., Erzen, I., and Ohlendieck, K. (2004) 'Early effects of denervation on calcium-handling proteins in skeletal muscle'. International Journal of Molecular Medicine, 13 :767-772.
	2004	Lohan, J. and Ohlendieck, K. (2004) 'Drastic reduction in the luminal calcium-binding proteins calsequestrin and sarcalumenin in dystrophin-deficient cardiac muscle'. Biochimica et biophysica acta, 1689 :252-258. [Full-Text]
	2003	Ryan, M., Butler-Browne, G., Erzen, I., Mouly, V., Thornell, L.-E., Wernig, A., and Ohlendieck, K. (2003) 'Persistent expression of the alpha-1S dihydropyridine receptor in aged human skeletal muscle: Implications for the excitation-contraction uncoupling hypothesis of sarcopenia'. International Journal of Molecular Medicine, 11 :425-434.

Conference Contribution

	Year	Publication
	2009	(2009) Proteomics of diabetes-induced muscle weakness International Symposium of Molecular Medicine Athens, Greece, .
	2009	(2009) Proteomics of muscular dystrophy XXXVIII European Muscle Conference Lille, France, .
	2009	Dr. Simon Whitehall (2009) The HIRA Histone Chaperone: A Global Regulator of Institute of Cell and Molecular Biosciences, Newca, Science, Biology, .
	2009	Dr Paul Bowyer (2009) Death, Taxes and Aspergillus - The Inevitability o School of Translational Medicine, University of Ma, Science, Biology, .
	2009	Professor Elodie Ghedin (2009) The Genesis of Influenza Virus Diversity Division of Infectious Diseases, University of Pit, Science, Biology, .
	2009	(2009) Biomarker signature of age-related muscle weakness American Association of Clinical Chemists Meeting Chicago, IL, USA, .
	2009	Professor Rosemary O'Connor (2009) The Insulin-like Growth Factor System in Health an Department of Biochemistry, University College Cor, Science, Biology, .
	2009	Professor Channapatna S. Prakash (2009) Challenges in the Adoption of Agribiotechnology in Dept. of Agricultural & Environmental Sciences, Tu, Science, Biology, .
	2009	Dr. Clara Redondo (2009) Retinol Binding Protein Interactions Marie Curie Laboratory for Membrane Proteins NUI M, Science, Biology, .
	2009	(2009) Experimental exon skipping therapy Annual Meeting, Muscular Dystrophy Ireland Dublin, .
	2009	Dr. Thomas Ritter (2009) Gene- and Cell Therapeutic Applications for the Pr REMEDI/NUI Galway, Science, Biology, .
	2009	Dr. Ewen Mullins (2009) Are GM Crops Relevant to Ireland's Agriculture? Biotechnology Centre, Teagasc Crops Research Centr, Science, Biology, .
	2009	Dr. Brian Burke (2009) Targeted Genome Editing in Mammalian Cells Using E Sigma Life Sciences, Dorset, UK, Science, Biology, .
	2009	Professor Mike Lehane (2009) Tsetse Flies and Trypanosomes - Africa's Bane or A Vector Group, Liverpool School of Tropical Medicin, Science, Biology, .
	2009	(2009) Proteomic profiling of muscle aging 1st Congress on Analytical Proteomics Lisboa, Portugal, .
	2009	Professor Thomas Ostenfeld Larsen (2009) Biotechnology and Analytical Natural Product Chemi Department of Systems Biology, Center for Microbia, Science, Biology, .
	2009	Dr. Adam Claridge-Chang (2009) Writing Memories with Light-Addressable Reinforcem Nuffield Department of Clinical Medicine, Universi, Science, Biology, .
	2009	Professor Elodie Ghedin (2009) The filaria /Brugia malayi/ and its Wolbachia endo Division of Infectious Diseases, University of Pit, Science, Biology, .
	2009	Professor John Parkinson (2009) HBiological Networks: Just How do They Evolve? Hospital for the Sick Children, Toronto, Canada, Science, Biology, .
	2009	(2009) Proteomic profiling of x-linked muscular dystrophy European Seating Symposium 2009 Dublin, .
	2009	Dr. Sandra O'Neill (2009) The Immunosuppressive Action of Helminth Molecules School of Nursing, DCU, Science, Biology, .

Book Review

	Year	Publication
	2013	Ohlendieck, K. (2013) On-membrane digestion technology for muscle proteomics. BREV
	2013	Ohlendieck, K. (2013) Proteomics of exercise-induced skeletal muscle adaptations. BREV
	2012	Ohlendieck, K. (2012) Proteomic profiling of skeletal muscle plasticity. BREV
	2012	Ohlendieck, K. (2012) Organelle proteomics in skeletal muscle biology. BREV
	2007	Doran, P., Gannon, J., O’Connell, K. and Ohlendieck, K. (2007) Proteomic profiling of aged and pathological skeletal muscle. BREV

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