World-class research based on a distinctive, interdisciplinary approach to the natural sciences, social sciences, engineering and technology, and the arts and humanities.
The MU International Office is the first point of contact for international students applying for full-degree, Erasmus, Study Abroad, and Summer School programmes, and supports MU students who wish to study abroad.
Prof. Kevin Kavanagh graduated with a BSc (Joint Honours) degree in Biology and Chemistry and undertook a PhD in Microbiology. He undertook postdoctoral research in projects in Maynooth and University of Kuwait, and the National Cell and Tissue Culture Centre in Dublin City University. He was appointed as a Lecturer in 1995 and promoted to Senior Lecturer in 2002 and to Professor in 2016. He was appointed as a visiting Lecturer in Medical Mycology at Queen's University Belfast in 2009.
Book Chapter
Year
Publication
2011
Kavanagh, K (2011) 'Fungal Fermentations Systems and Products' In: FUNGI: BIOLOGY AND APPLICATIONS, 2ND EDITION. OXFORD : BLACKWELL SCIENCE PUBL.
2011
Kavanagh K. (2011) 'Fungal Fermentations Systems and Products' In: Fungi: Biology and Applications. [DOI]
2007
Renwick J.; Kavanagh K. (2007) 'Insects as models for studying the virulence of fungal pathogens of humans' In: New Insights in Medical Mycology. [DOI]
2007
Geraghty P.; Kavanagh K. (2007) 'Extraction and Detection of DNA and RNA from Yeast' In: Medical Mycology: Cellular and Molecular Techniques. [DOI]
2007
Kavanagh K.; Sullivan D. (2007) 'Fungi' In: Hugo and Russell's Pharmaceutical Microbiology: Seventh Edition. [DOI]
2006
Geraghty, P & Kavanagh, K. (2006) 'Extraction and Detection of DNA and RNA from Yeast' In: K. Kavanagh(Eds.). Medical Mycology: Cellular and Molecular Techniques. . Chichester, UK : Wiley & Co. Ltd.
2005
Kavanagh K. (2005) 'Fungal Fermentation Systems and Products' In: Fungi: Biology and Applications. [DOI]
2005
Kavanagh, K. (2005) 'Fungal Fermentation: Technology and Products' In: K. Kavanagh(Eds.). Fungi: Biology and Applications. Chichester, UK : Wiley & Co. Ltd.
2004
Kavanagh, K. & Sullivan, D. (2004) 'Biology of Microorganisms: Fungi' In: S. Denyer, N.A. Hodges & S. Gorman(Eds.). Pharmaceutical Microbiology. : Blackwells.
2003
Kavanagh K & Sullivan D (2003) 'Yeasts and Molds' In: S. Gorman & N.A. Hodges(Eds.). Pharmaceutical Microbiology.
2002
Kavanagh, K. & Whittaker P.A. (2002) 'Protoplasts' In: Encyclopedia of Molecular Biology. New York : Wiley and Sons.
2002
Kavanagh K., & Whittaker P. (2002) 'Protoplast Fusion' In: Encyclopedia of Molecular Biology. New York : Wiley and Sons.
1994
Weedle,R. K. Carroll, K. Kavanagh, R O'Kennedy, & M. Clynes. (1994) 'Development of a Hybridoma Cloning Medium' In: R. Spier, J. Griffiths & W. Berthold(Eds.). Animal Cell Technology: Products of Today, Prospects for Tomorrow. Oxford : Butterworth-Heinemann.
Peer Reviewed Journal
Year
Publication
2020
Margalit A.; Carolan J.C.; Sheehan D.; Kavanagh K. (2020) 'The Aspergillus fumigatus Secretome Alters the Proteome of Pseudomonas aeruginosa to Stimulate Bacterial Growth: Implications for Co-infection'. Molecular and Cellular Proteomics, 19 (8):1346-1359. [DOI][Full-Text]
2020
Kosanovic D.; Grogan H.; Kavanagh K. (2020) 'Exposure of Agaricus bisporus to Trichoderma aggressivum f. europaeum leads to growth inhibition and induction of an oxidative stress response'. Fungal Biology, . [DOI][Full-Text]
2020
Rochford G.; Molphy Z.; Kavanagh K.; McCann M.; Devereux M.; Kellett A.; Howe O. (2020) 'Cu(ii) phenanthroline-phenazine complexes dysregulate mitochondrial function and stimulate apoptosis'. Metallomics, 12 (1):65-78. [DOI][Full-Text]
2020
Gandra R.M.; McCarron P.; Viganor L.; Fernandes M.F.; Kavanagh K.; McCann M.; Branquinha M.H.; Santos A.L.S.; Howe O.; Devereux M. (2020) 'In vivo Activity of Copper(II), Manganese(II), and Silver(I) 1,10-Phenanthroline Chelates Against Candida haemulonii Using the Galleria mellonella Model'. Frontiers in Microbiology, 11 . [DOI][Full-Text]
2020
Ajdidi A.; Sheehan G.; Kavanagh K. (2020) 'Exposure of aspergillus fumigatus to atorvastatin leads to altered membrane permeability and induction of an oxidative stress response'. Journal Of Fungi, 6 (2). [DOI][Full-Text]
2020
Martin H.; Kavanagh K.; Velasco-Torrijos T. (2020) 'Targeting adhesion in fungal pathogen Candida albicans'. Future Medicinal Chemistry, . [DOI][Full-Text]
2020
Sheehan, G; Tully, L; Kavanagh, KA (2020) 'Candida albicans increases the pathogenicity of Staphylococcus aureus during polymicrobial infection of Galleria mellonella larvae'. Microbiology - Society for General Microbiology, 166 :375-385. [DOI][Full-Text]
2020
Principe, L; Vecchio, G; Sheehan, G; Kavanagh, K; Morroni, G; Viaggi, V; di Masi, A; Giacobbe, DR; Luzzaro, F; Luzzati, R; Di Bella, S (2020) 'Zinc Chelators as Carbapenem Adjuvants for Metallo-beta-Lactamase-Producing Bacteria: In Vitro and In Vivo Evaluation'. Microbial Drug Resistance, . [DOI][Full-Text]
2020
Sheehan G.; Konings M.; Lim W.; Fahal A.; Kavanagh K.; van de Sande W.W.J. (2020) 'Proteomic analysis of the processes leading to Madurella mycetomatis grain formation in Galleria mellonella larvae'. PLoS Neglected Tropical Diseases, 14 (4). [DOI][Full-Text]
2019
Sheehan G.; Kavanagh K. (2019) 'Proteomic analysis of the responses of Candida albicans during infection of Galleria mellonella larvae'. Journal Of Fungi, 5 (1). [DOI][Full-Text]
2019
Hasan P.; Pillalamarri V.; Aneja B.; Irfan M.; Azam M.; Perwez A.; Maguire R.; Yadava U.; Kavanagh K.; Daniliuc C.; Ahmad M.; Rizvi M.; Rizwanul Haq Q.; Addlagatta A.; Abid M. (2019) 'Synthesis and mechanistic studies of diketo acids and their bioisosteres as potential antibacterial agents'. European Journal of Medicinal Chemistry, 163 :67-82. [DOI][Full-Text]
2019
Sheehan G.; Nagl M.; Kavanagh K. (2019) 'Exposure to n-chlorotaurine induces oxidative stress responses in aspergillus fumigatus'. Journal of Medical Microbiology, 68 (2):279-288. [DOI][Full-Text]
2019
Margalit A; Kavanagh K; Carolan JC; (2019) 'Characterization of the proteomic response of A549 cells following sequential exposure to Aspergillus fumigatus and Pseudomonas aeruginosa'. Journal of Proteome Research, 19 (1):279-291. [DOI][Full-Text]
2019
Wani, FA; Amaduddin; Aneja, B; Sheehan, G; Kavanagh, K; Ahmad, R; Abid, M; Patel, R (2019) 'Synthesis of Novel Benzimidazolium Gemini Surfactants and Evaluation of Their Anti-Candida Activity'. Acs Omega, 4 :11871-11879. [DOI][Full-Text]
2019
Kosanovic, D; Sheehan, G; Grogan, H; Kavanagh, K (2019) 'Characterisation of the interaction of Pseudomonas putida and Pseudomonas tolaasii with Trichoderma aggressivum'. European Journal of Plant Pathology, . [DOI][Full-Text]
2019
Mc Namara L.; Dolan S.; Walsh J.; Stephens J.; Glare T.; Kavanagh K.; Griffin C. (2019) 'Oosporein, an abundant metabolite in Beauveria caledonica, with a feedback induction mechanism and a role in insect virulence'. Fungal Biology, 123 (8):601-610. [DOI][Full-Text]
2019
D'Arcy K.; Doyle A.; Kavanagh K.; Ronconi L.; Fresch B.; Montagner D. (2019) 'Stability of antibacterial Te(IV)compounds: A combined experimental and computational study'. Journal of Inorganic Biochemistry, 198 . [DOI][Full-Text]
2019
Ajdidi A.; Sheehan G.; Abu Elteen K.; Kavanagh K. (2019) 'Assessment of the in vitro and in vivo activity of atorvastatin against Candida albicans'. Journal of Medical Microbiology, 68 (10):1497-1506. [DOI][Full-Text]
2019
Ude Z.; Kavanagh K.; Twamley B.; Pour M.; Gathergood N.; Kellett A.; Marmion C. (2019) 'A new class of prophylactic metallo-antibiotic possessing potent anti-cancer and anti-microbial properties'. Dalton Transactions, 48 (24):8578-8593. [DOI][Full-Text]
2019
O'Beirne C.; Alhamad N.; Ma Q.; Müller-Bunz H.; Kavanagh K.; Butler G.; Zhu X.; Tacke M. (2019) 'Synthesis, structures and antimicrobial activity of novel NHC∗- and Ph3P-Ag(I)-Benzoate derivatives'. Inorganica Chimica Acta, 486 :294-303. [DOI][Full-Text]
2019
Sheehan G.; Dixon A.; Kavanagh K. (2019) 'Utilization of galleria mellonella larvae to characterize the development of staphylococcus aureus infection'. Microbiology - Society for General Microbiology, 165 (8):863-875. [DOI][Full-Text]
2018
Sheehan G.; Garvey A.; Croke M.; Kavanagh K. (2018) 'Innate humoral immune defences in mammals and insects: The same, with differences ?'. Virulence, 9 (1):1625-1639. [DOI][Full-Text]
2018
Martin H; Govern MM; Abbey L; Gilroy A; Mullins S; Howell S; Kavanagh K; Velasco-Torrijos T; (2018) 'Inhibition of adherence of the yeast Candida albicans to buccal epithelial cells by synthetic aromatic glycoconjugates'. European Journal of Medicinal Chemistry, 160 . [DOI][Full-Text]
2018
Surlis C; Carolan JC; Coffey M; Kavanagh K; (2018) 'Quantitative proteomics reveals divergent responses in Apis mellifera worker and drone pupae to parasitization by Varroa destructor'. Journal of Insect Physiology, . [DOI][Full-Text]
2018
O'Beirne C.; Althani H.; Dada O.; Cassidy J.; Kavanagh K.; Müller-Bunz H.; Ortin Y.; Zhu X.; Tacke M. (2018) 'Novel derivatives of the antibiotic NHC–Ag(I) drug candidate SBC3: Synthesis, biological evaluation and109Ag NMR studies'. Polyhedron, 149 :95-103. [DOI][Full-Text]
2018
Aneja B.; Azam M.; Alam S.; Perwez A.; Maguire R.; Yadava U.; Kavanagh K.; Daniliuc C.; Rizvi M.; Haq Q.; Abid M. (2018) 'Natural Product-Based 1,2,3-Triazole/Sulfonate Analogues as Potential Chemotherapeutic Agents for Bacterial Infections'. Acs Omega, 3 (6):6912-6930. [DOI][Full-Text]
2018
Sheehan G.; Clarke G.; Kavanagh K. (2018) 'Characterisation of the cellular and proteomic response of Galleria mellonella larvae to the development of invasive aspergillosis'. BMC Microbiology, 18 (1). [DOI][Full-Text]
2018
Barrett S.; Delaney S.; Kavanagh K.; Montagner D. (2018) 'Evaluation of in vitro and in vivo antibacterial activity of novel Cu(II)-steroid complexes'. Inorganica Chimica Acta, 479 :261-265. [DOI][Full-Text]
2018
McCarron P.; McCann M.; Devereux M.; Kavanagh K.; Skerry C.; Karakousis P.; Aor A.; Mello T.; Santos A.; Campos D.; Pavan F. (2018) 'Unprecedented in vitro antitubercular activitiy of manganese(II) complexes containing 1,10-phenanthroline and dicarboxylate ligands: Increased activity, superior selectivity, and lower toxicity in comparison to their copper(II) analogs'. Frontiers in Microbiology, 9 (JUL). [DOI][Full-Text]
2018
Maher A.; Staunton K.; Kavanagh K. (2018) 'Analysis of the effect of temperature on protein abundance in Demodex-associated Bacillus oleronius'. Pathogens and Disease, 76 (4). [DOI][Full-Text]
2018
Rochford G.; Molphy Z.; Browne N.; Surlis C.; Devereux M.; McCann M.; Kellett A.; Howe O.; Kavanagh K. (2018) 'In-vivo evaluation of the response of Galleria mellonella larvae to novel copper(II) phenanthroline-phenazine complexes'. Journal of Inorganic Biochemistry, 186 :135-146. [DOI][Full-Text]
2018
Namara LM; Griffin CT; Fitzpatrick D; Kavanagh K; Carolan JC; (2018) 'The effect of entomopathogenic fungal culture filtrate on the immune response and haemolymph proteome of the large pine weevil, Hylobius abietis'. Insect Biochemistry and Molecular Biology, . [DOI][Full-Text]
2018
Mc Namara L.; Kapranas A.; Williams C.; O’Tuama P.; Kavanagh K.; Griffin C. (2018) 'Efficacy of entomopathogenic fungi against large pine weevil, Hylobius abietis, and their additive effects when combined with entomopathogenic nematodes'. Journal of Pest Science, :1-13. [DOI][Full-Text]
2018
Sheehan G.; Bergsson G.; McElvaney N.; Reeves E.; Kavanagh K. (2018) 'The human cathelicidin antimicrobial peptide LL-37 promotes the growth of the pulmonary pathogen Aspergillus fumigatus'. Infection and Immunity, 86 (7). [DOI][Full-Text]
Reddy A; Sangenito LS; Guedes AA; Branquinha MH; Kavanagh K; McGinley J; Dos Santos ALS; Velasco-Torrijos T; (2017) 'Glycosylated metal chelators as anti-parasitic agents with tunable selectivity'. Dalton Transactions, 46 (16). [DOI][Full-Text]
2017
Maguire R.; Kunc M.; Hyrsl P.; Kavanagh K. (2017) 'Caffeine administration alters the behaviour and development of Galleria mellonella larvae'. Neurotoxicology and Teratology, 64 :37-44. [DOI][Full-Text]
2017
Maguire R.; Kunc M.; Hyrsl P.; Kavanagh K. (2017) 'Analysis of the acute response of Galleria mellonella larvae to potassium nitrate'. Comparative Biochemistry and Physiology, Part C, 195 :44-51. [DOI][Full-Text]
2017
Vellé A.; Maguire R.; Kavanagh K.; Sanz Miguel P.; Montagner D. (2017) 'Steroid–AuI–NHC Complexes: Synthesis and Antibacterial Activity'. ChemMedChem, 12 (11):841-844. [DOI][Full-Text]
2017
Sheehan G.; Kavanagh K. (2017) 'Analysis of the early cellular and humoral responses of Galleria mellonella larvae to infection by Candida albicans'. Virulence, :1-10. [DOI][Full-Text]
2017
Mc Namara, L; Carolan, JC; Griffin, CT; Fitzpatrick, D; Kavanagh, K (2017) 'The effect of entomopathogenic fungal culture filtrate on the immune response of the greater wax moth, Galleria mellonella'. Journal of Insect Physiology, 100 :82-92. [DOI][Full-Text]
2017
O’Brien M.; Kavanagh K.; Grogan H. (2017) 'Detection of Trichoderma aggressivum in bulk phase III substrate and the effect of T. aggressivum inoculum, supplementation and substrate-mixing on Agaricus bisporus yields'. European Journal of Plant Pathology, 147 (1):199-209. [DOI][Full-Text]
2016
Mujahid M., Trendafilova N., Foltyn-Kia A., Rosair G., Kavanagh K., Walsh M., McClean S., Creaven. BS, Georgieva I. (2016) 'Synthesis of Silver(I) Complexes Of Coumarin-Based Ligands And Their Phenanthroline Adducts: Structural Characterisation and Antimicrobial Activity'. Journal of Inorganic Biochemistry, 163 :53-57. [Full-Text]
2016
Velikova N; Kavanagh K; Wells JM; (2016) 'Evaluation of Galleria mellonella larvae for studying the virulence of Streptococcus suis'. BMC Microbiology, 16 (1). [DOI][Full-Text]
2016
O’Brien M, Kavanagh K, Grogan H (2016) 'Detection of Trichoderma aggressivum in bulk Phase III substrate and the effect of T. aggressivum inoculum, supplementation and substrate-mixing on Agaricus bisporus yields'. European Journal of Plant Pathology, 147 :199-209. [Full-Text]
2016
Mujahid M.; Trendafilova N.; Arfa-Kia A.; Rosair G.; Kavanagh K.; Devereux M.; Walsh M.; McClean S.; Creaven B.; Georgieva I. (2016) 'Novel silver(I) complexes of coumarin oxyacetate ligands and their phenanthroline adducts: Biological activity, structural and spectroscopic characterisation'. Journal of Inorganic Biochemistry, 163 :53-67. [DOI][Full-Text]
2016
Dolan N, Gavin DP, Eshwika A, Kavanagh K, McGinley J and Stephens JC (2016) 'Synthesis, antibacterial and anti-MRSA activity, in vivo toxicity and a structure-activity relationship study of a quinoline thiourea'. Bioorganic and Medicinal Chemistry, 26 :630-635. [Full-Text]
2016
Surlis C.; Carolan J.; Coffey M.; Kavanagh K. (2016) 'Proteomic analysis of Bayvarol® resistance mechanisms in the honey bee parasite Varroa destructor'. Journal of Apicultural Research, :1-16. [DOI][Full-Text]
2016
Maguire R.; Duggan O.; Kavanagh K. (2016) 'Evaluation of Galleria mellonella larvae as an in vivo model for assessing the relative toxicity of food preservative agents'. Cell Biology and Toxicology, 32 (3):209-216. [DOI][Full-Text]
2016
Aneja B.; Irfan M.; Kapil C.; Jairajpuri M.; Maguire R.; Kavanagh K.; Rizvi M.; Manzoor N.; Azam A.; Abid M. (2016) 'Effect of novel triazole-amino acid hybrids on growth and virulence of Candida species: in vitro and in vivo studies'. Organic and Biomolecular Chemistry, 14 (45):10599-10619. [DOI][Full-Text]
2016
McMahon F.; Banville N.; Bergin D.; Smedman C.; Paulie S.; Reeves E.; Kavanagh K. (2016) 'Activation of Neutrophils via IP3Pathway Following Exposure to Demodex-Associated Bacterial Proteins'. Journal of Inflammation, 39 (1):425-433. [DOI][Full-Text]
2016
Dolan, N; Gavin, DP; Eshwika, A; Kavanagh, K; McGinley, J; Stephens, JC (2016) 'Synthesis, antibacterial and anti-MRSA activity, in vivo toxicity and a structure-activity relationship study of a quinoline thiourea'. Bioorganic and Medicinal Chemistry Letters, 26 :630-635. [DOI][Full-Text]
2015
Browne, N; Surlis, C; Maher, A; Gallagher, C; Carolan, JC; Clynes, M; Kavanagh, K (2015) 'Prolonged pre-incubation increases the susceptibility of Galleria mellonella larvae to bacterial and fungal infection'. Virulence, 6 :458-465. [DOI][Full-Text]
2015
Maurer, E; Browne, N; Surlis, C; Jukic, E; Moser, P; Kavanagh, K; Lass-Florl, C; Binder, U (2015) 'Galleria mellonella as a host model to study Aspergillus terreus virulence and amphotericin B resistance'. Virulence, 6 :603-610. [DOI][Full-Text]
2014
Jarmuda, S; McMahon, F; Zaba, R; O'Reilly, N; Jakubowicz, O; Holland, A; Szkaradkiewicz, A; Kavanagh, K (2014) 'Correlation between serum reactivity to Demodex-associated Bacillus oleronius proteins, and altered sebum levels and Demodex populations in erythematotelangiectatic rosacea patients'. Journal of Medical Microbiology, 63 :258-262. [DOI][Full-Text]
2014
Dolan, N; McGinley, J; Stephens, JC; Kavanagh, K; Hurley, D; Maher, NJ (2014) 'Synthesis, characterisation and antimicrobial studies of organotin(IV) complexes with 1,10-phenanthroline derivatives'. Inorganica Chimica Acta, 409 :276-284. [DOI][Full-Text]
2014
Sullivan, M; Kia, AFA; Long, M; Walsh, M; Kavanagh, K; McClean, S; Creaven, BS (2014) 'Isolation and characterisation of silver(I) complexes of substituted coumarin-4-carboxylates which are effective against Pseudomonas aeruginosa biofilms'. Polyhedron, 67 :549-559. [DOI][Full-Text]
2014
O'Brien, M; Grogan, H; Kavanagh, K (2014) 'Proteomic response of Trichoderma aggressivum f. europaeum to Agaricus bisporus tissue and mushroom compost'. Fungal Biology, 118 :785-791. [DOI][Full-Text]
2014
McMahon, FW; Gallagher, C; O'Reilly, N; Clynes, M; O'Sullivan, F; Kavanagh, K (2014) 'Exposure of a Corneal Epithelial Cell Line (hTCEpi) to Demodex-Associated Bacillus Proteins Results in an Inflammatory Response'. Investigative Ophthalmology & Visual Science, 55 . [DOI][Full-Text]
2014
Browne, N; Surlis, C; Kavanagh, K (2014) 'Thermal and physical stresses induce a short-term immune priming effect in Galleria mellonella larvae'. Journal of Insect Physiology, 63 :21-26. [DOI][Full-Text]
2014
Browne, N; Hackenberg, F; Streciwilk, W; Tacke, M; Kavanagh, K (2014) 'Assessment of in vivo antimicrobial activity of the carbene silver(I) acetate derivative SBC3 using Galleria mellonella larvae'. BioMetals, 27 :745-752. [DOI][Full-Text]
2013
McCann, M; Curran, R; Ben-Shoshan, M; McKee, V; Devereux, M; Kavanagh, K; Kellett, A (2013) 'Synthesis, structure and biological activity of silver(I) complexes of substituted imidazoles'. Polyhedron, 56 :180-188. [DOI][Full-Text]
2013
O'Keeffe, G; Jochl, C; Kavanagh, K; Doyle, S (2013) 'Extensive proteomic remodeling is induced by eukaryotic translation elongation factor 1B gamma deletion in Aspergillus fumigatus'. Protein Science, 22 :1612-1622. [DOI][Full-Text]
2013
Eshwika, A; Kelly, J; Fallon, JP; Kavanagh, K (2013) 'Exposure of Aspergillus fumigatus to caspofungin results in the release, and de novo biosynthesis, of gliotoxin'. Medical Mycology, 51 :121-127. [DOI][Full-Text]
2013
O'Keeffe G.; Jöchl C.; Kavanagh K.; Doyle S. (2013) 'Extensive proteomic remodeling is induced by eukaryotic translation elongation factor 1Bc deletion in Aspergillus fumigatus'. Protein Science, 22 (11):1612-1622. [DOI][Full-Text]
2013
Smith, A; McCann, M; Kavanagh, K (2013) 'Proteomic analysis of the proteins released from Staphylococcus aureus following exposure to Ag(I)'. Toxicology in Vitro, 27 :1644-1648. [DOI][Full-Text]
2013
McGinley, J; McCann, M; Ni, KJ; Tallon, T; Kavanagh, K; Devereux, M; Ma, XM; McKee, V (2013) 'Imidazole Schiff base ligands: Synthesis, coordination complexes and biological activities'. Polyhedron, 55 :169-178. [DOI][Full-Text]
2013
McCann, M; McGinley, J; Ni, K; O'Connor, M; Kavanagh, K; Mckee, V; Colleran, J; Devereux, M; Gathergood, N; Barron, N; Prisecaru, A; Kellett, A (2013) 'A new phenanthroline-oxazine ligand: synthesis, coordination chemistry and atypical DNA binding interaction'. Chemical Communications, 49 :2341-2343. [DOI][Full-Text]
2013
Thati, B; Noble, A; Creaven, BS; Walsh, M; McCann, M; Kavanagh, K; Devereux, M; Egan, DA (2013) 'A study of the role of apoptotic cell death and cell cycle events mediating the mechanism of action of 6-hydroxycoumarin-3-carboxylatosilver in human malignant hepatic cells (Retraction of vol 250, pg 128, 2007)'. Cancer Letters, 337 :146-146. [DOI]
2012
Gallagher, L; Owens, RA; Dolan, SK; O'Keeffe, G; Schrettl, M; Kavanagh, K; Jones, GW; Doyle, S (2012) 'The Aspergillus fumigatus Protein GliK Protects against Oxidative Stress and Is Essential for Gliotoxin Biosynthesis'. Eukaryotic Cell, 11 :1226-1238. [DOI][Full-Text]
2012
O'Reilly, N; Menezes, N; Kavanagh, K (2012) 'Positive correlation between serum immunoreactivity to Demodex-associated Bacillus proteins and erythematotelangiectatic rosacea'. British Journal of Dermatology, 167 :1032-1036. [DOI]
2012
Carberry, S; Molloy, E; Hammel, S; O'Keeffe, G; Jones, GW; Kavanagh, K; Doyle, S (2012) 'Gliotoxin effects on fungal growth: Mechanisms and exploitation'. Fungal Genetics and Biology, 49 :302-312. [DOI][Full-Text]
2012
O'Reilly, N; Bergin, D; Reeves, EP; McElvaney, NG; Kavanagh, K (2012) 'Demodex-associated bacterial proteins induce neutrophil activation'. British Journal of Dermatology, 166 :753-760. [DOI][Full-Text]
2012
Banville, N; Browne, N; Kavanagh, K (2012) 'Effect of nutrient deprivation on the susceptibility of Galleria mellonella larvae to infection'. Virulence, 3 :497-503. [DOI][Full-Text]
2012
McCann, M; Santos, ALS; da Silva, BA; Romanos, MTV; Pyrrho, AS; Devereux, M; Kavanagh, K; Fichtner, I; Kellett, A (2012) 'In vitro and in vivo studies into the biological activities of 1,10-phenanthroline, 1,10-phenanthroline-5,6-dione and its copper(II) and silver(I) complexes'. Toxicology Research, 1 :47-54. [DOI][Full-Text]
2012
McCann M.; Kellett A.; Kavanagh K.; Devereux M.; Santos A. (2012) 'Deciphering the antimicrobial activity of phenanthroline chelators'. Current Medicinal Chemistry, 19 (17):2703-2714.
2012
Smith, A; Rowan, R; McCann, M; Kavanagh, K (2012) 'Exposure of Staphylococcus aureus to silver(I) induces a short term protective response'. BioMetals, 25 :611-616. [DOI][Full-Text]
2012
Coughlan, CA; Chotirmall, SH; Renwick, J; Hassan, T; Low, TB; Bergsson, G; Eshwika, A; Bennett, K; Dunne, K; Greene, CM; Gunaratnam, C; Kavanagh, K; Logan, PM; Murphy, P; Reeves, EP; McElvaney, NG (2012) 'The Effect of Aspergillus fumigatus Infection on Vitamin D Receptor Expression in Cystic Fibrosis'. American Journal of Respiratory and Critical Care Medicine, 186 :999-1007. [DOI][Full-Text]
2012
O'Hanlon, KA; Gallagher, L; Schrettl, M; Jochl, C; Kavanagh, K; Larsen, TO; Doyle, S (2012) 'Nonribosomal Peptide Synthetase Genes pesL and pes1 Are Essential for Fumigaclavine C Production in Aspergillus fumigatus'. Applied And Environmental Microbiology, 78 :3166-3176. [DOI][Full-Text]
2012
O'Reilly, N; Gallagher, C; Katikireddy, KR; Clynes, M; O'Sullivan, F; Kavanagh, K (2012) 'Demodex-Associated Bacillus Proteins Induce an Aberrant Wound Healing Response in a Corneal Epithelial Cell Line: Possible Implications for Corneal Ulcer Formation in Ocular Rosacea'. Investigative Ophthalmology & Visual Science, 53 :3250-3259. [DOI][Full-Text]
2012
McCann, M; Curran, R; Ben-Shoshan, M; McKee, V; Tahir, AA; Devereux, M; Kavanagh, K; Creaven, BS; Kellett, A (2012) 'Silver(I) complexes of 9-anthracenecarboxylic acid and imidazoles: synthesis, structure and antimicrobial activity'. Dalton Transactions, 41 :6516-6527. [DOI][Full-Text]
2011
Davis, C; Gordon, N; Murphy, S; Singh, I; Kavanagh, K; Carberry, S; Doyle, S (2011) 'Single-pot derivatisation strategy for enhanced gliotoxin detection by HPLC and MALDI-ToF mass spectrometry'. Analytical and Bioanalytical Chemistry, 401 :2519-2529. [DOI][Full-Text]
2011
Kelly, J; Kavanagh, K (2011) 'Caspofungin primes the immune response of the larvae of Galleria mellonella and induces a non-specific antimicrobial response'. Journal of Medical Microbiology, 60 :189-196. [DOI][Full-Text]
2011
Kellett, A; O'Connor, M; McCann, M; Howe, O; Casey, A; McCarron, P; Kavanagh, K; McNamara, M; Kennedy, S; May, DD; Skell, PS; O'Shea, D; Devereux, M (2011) 'Water-soluble bis(1,10-phenanthroline) octanedioate Cu2+ and Mn2+ complexes with unprecedented nano and picomolar in vitro cytotoxicity: promising leads for chemotherapeutic drug development'. MedChemComm, 2 :579-584. [DOI][Full-Text]
Davis, C; Carberry, S; Schrettl, M; Singh, I; Stephens, JC; Barry, SM; Kavanagh, K; Challis, GL; Brougham, D; Doyle, S (2011) 'The Role of Glutathione S-Transferase GliG in Gliotoxin Biosynthesis in Aspergillus fumigatus'. Chemistry and Biology, 18 :542-552. [DOI][Full-Text]
2011
Fallon, JP; Reeves, EP; Kavanagh, K (2011) 'The Aspergillus fumigatus toxin fumagillin suppresses the immune response of Galleria mellonella larvae by inhibiting the action of haemocytes'. Microbiology - Society for General Microbiology, 157 :1481-1488. [DOI][Full-Text]
2011
Griffith, DM; Duff, B; Suponitsky, KY; Kavanagh, K; Morgan, MP; Egan, D; Marmion, CJ (2011) 'Novel trans-platinum complexes of the histone deacetylase inhibitor valproic acid; synthesis, in vitro cytotoxicity and mutagenicity'. Journal of Inorganic Biochemistry, 105 :793-799. [DOI][Full-Text]
2011
Banville, N; Fallon, J; McLoughlin, K; Kavanagh, K (2011) 'Disruption of haemocyte function by exposure to cytochalasin b or nocodazole increases the susceptibility of Galleria mellonella larvae to infection'. Microbes and Infection, 13 :1191-1198. [DOI]
2011
O'Hanlon, KA; Cairns, T; Stack, D; Schrettl, M; Bignell, EM; Kavanagh, K; Miggin, SM; O'Keeffe, G; Larsen, TO; Doyle, S (2011) 'Targeted Disruption of Nonribosomal Peptide Synthetase pes3 Augments the Virulence of Aspergillus fumigatus'. Infection and Immunity, 79 :3978-3992. [DOI][Full-Text]
2011
Fallon, JP; Troy, N; Kavanagh, K (2011) 'Pre-exposure of Galleria mellonella larvae to different doses of Aspergillus fumigatus conidia causes differential activation of cellular and humoral immune responses'. Virulence, 2 :413-421. [DOI][Full-Text]
2011
Costello, A; Herbert, G; Fabunmi, L; Schaffer, K; Kavanagh, KA; Caraher, EM; Callaghan, M; McClean, S (2011) 'Virulence of an emerging respiratory pathogen, genus Pandoraea, in vivo and its interactions with lung epithelial cells'. Journal of Medical Microbiology, 60 :289-299. [DOI][Full-Text]
2010
Creaven, BS; Duff, B; Egan, DA; Kavanagh, K; Rosair, G; Thangella, VR; Walsh, M (2010) 'Anticancer and antifungal activity of copper(II) complexes of quinolin-2(1H)-one-derived Schiff bases'. Inorganica Chimica Acta, 363 :4048-4058. [DOI][Full-Text]
2010
Kelly, J; Kavanagh, K (2010) 'Proteomic analysis of proteins released from growth-arrested Candida albicans following exposure to caspofungin'. Medical Mycology, 48 :598-605. [DOI][Full-Text]
2010
Rowan, R; McCann, M; Kavanagh, K (2010) 'Analysis of the response of Candida albicans cells to Silver(I)'. Medical Mycology, 48 :498-505. [DOI][Full-Text]
2010
Li, JJ; O'Reilly, N; Sheha, H; Katz, R; Raju, VK; Kavanagh, K; Tseng, SCG (2010) 'Correlation between Ocular Demodex Infestation and Serum Immunoreactivity to Bacillus Proteins in Patients with Facial Rosacea'. Ophthalmology, 117 :870-48. [DOI][Full-Text]
2010
Fallon, JP; Reeves, EP; Kavanagh, K (2010) 'Inhibition of neutrophil function following exposure to the Aspergillus fumigatus toxin fumagillin'. Journal of Medical Microbiology, 59 :625-633. [DOI][Full-Text]
2010
Schrettl, M; Carberry, S; Kavanagh, K; Haas, H; Jones, GW; O'Brien, J; Nolan, A; Stephens, J; Fenelon, O; Doyle, S (2010) 'Self-Protection against Gliotoxin-A Component of the Gliotoxin Biosynthetic Cluster, GliT, Completely Protects Aspergillus fumigatus Against Exogenous Gliotoxin'. PLoS Pathogens, 6 . [DOI][Full-Text]
2010
Mowlds, P; Coates, C; Renwick, J; Kavanagh, K (2010) 'Dose-dependent cellular and humoral responses in Galleria mellonella larvae following beta-glucan inoculation'. Microbes and Infection, 12 :146-153. [DOI][Full-Text]
2009
Lacey N.; Kavanagh K.; Tseng S. (2009) 'Demodex mites in human diseases: Under the lash'. Biochemist, 31 (4):20-24. [Full-Text]
2009
Kelly, J; Rowan, R; Mccann, M; Kavanagh, K (2009) 'Exposure to caspofungin activates Cap and Hog pathways in Candida albicans'. Medical Mycology, 47 :697-706. [DOI][Full-Text]
2009
Rowan R.; Moran C.; McCann M.; Kavanagh K. (2009) 'Use of Galleria mellonella larvae to evaluate the in vivo anti-fungal activity of [Ag2(mal)(phen)3]'. BioMetals, 22 (3):461-467. [DOI][Full-Text]
2008
Mowlds, P; Kavanagh, K (2008) 'Effect of pre-incubation temperature on susceptibility of Galleria mellonella larvae to infection by Candida albicans'. Mycopathologia, 165 :5-12. [DOI][Full-Text]
2008
Mowlds, P; Barron, A; Kavanagh, K (2008) 'Physical stress primes the immune response of Galleria mellonella larvae to infection by Candida albicans'. Microbes and Infection, 10 :628-634. [DOI][Full-Text]
2007
Creaven B.; Egan D.; Karcz D.; Kavanagh K.; McCann M.; Mahon M.; Noble A.; Thati B.; Walsh M. (2007) 'Synthesis, characterisation and antimicrobial activity of copper(II) and manganese(II) complexes of coumarin-6,7-dioxyacetic acid (cdoaH2) and 4-methylcoumarin-6,7-dioxyacetic acid (4-MecdoaH2): X-ray crystal structures of [Cu(cdoa)(phen)2] · 8.8H2O and [Cu(4-Mecdoa)(phen)2] · 13H2O (phen = 1,10-phenanthroline)'. Journal of Inorganic Biochemistry, 101 (8):1108-1119. [DOI][Full-Text]
2007
Abu-Elteen K.; Hamad M.; Kavanagh K. (2007) 'Epsilometer test-based determination of susceptibility of clinically important Candida isolates to conventional antifungal agents'. Journal of Medical Sciences - Pakistan, 7 (3):374-382. [Full-Text]
2007
Curran, R; Lenehan, J; McCann, M; Kavanagh, K; Devereux, M; Egan, DA; Clifford, G; Keane, K; Creaven, BS; Mckee, V (2007) '[Ag-2(aca)(2)](n) and [Ag-4(aca)(4)(NH3)(2)] (acaH=9-anthracenecarboxylic acid): Synthesis, X-ray crystal structures, antimicrobial and anti-cancer activities'. Inorganic Chemistry Communication, 10 :1149-1153. [DOI][Full-Text]
2007
Thati, B; Noble, A; Rowan, R; Creaven, BS; Walsh, M; McCann, M; Egan, D; Kavanagh, K (2007) 'Mechanism of action of coumarin and silver(I)-coumarin complexes against the pathogenic yeast Candida albicans'. Toxicology in Vitro, 21 :801-808. [DOI][Full-Text]
2007
Lacey, N; Delaney, S; Kavanagh, K; Powell, FC (2007) 'Mite-related bacterial antigens stimulate inflammatory cells in rosacea'. British Journal of Dermatology, 157 :474-481. [DOI][Full-Text]
2007
Renwick, J; Reeves, EP; Wientjes, FB; Kavanagh, K (2007) 'Translocation of proteins homologous to human neutrophil p47(phox) and p67(phox) to the cell membrane in activated hemocytes of Galleria mellonella'. Developmental and Comparative Immunology, 31 :347-359. [DOI][Full-Text]
2007
Vickers, I; Reeves, EP; Kavanagh, KA; Doyle, S (2007) 'Isolation, activity and immunological characterisation of a secreted aspartic protease, CtsD, from Aspergillus fumigatus'. Protein Expression and Purification, 53 :216-224. [DOI][Full-Text]
2007
Abuskhuna, S; McCann, M; Briody, J; Devereux, M; Kavanagh, K; Kayal, N; McKee, V (2007) 'Synthesis and structure of metal complexes containing zwitterionic N-hydroxyimidazole ligands'. Polyhedron, 26 :4573-4580. [DOI][Full-Text]
2007
Creaven, BS; Egan, DA; Karcz, D; Kavanagh, K; McCann, M; Mahon, M; Noble, A; Thati, B; Walsh, M (2007) 'Synthesis, characterisation and antimicrobial activity of copper(II) and manganese(II) complexes of coumarin-6,7-dioxyacetic acid (cdoaH(2)) and 4-methylcoumarin-6,7-dioxyacetic acid (4-MecdoaH(2)): X-ray crystal structures of [Cu(cdoa)(phen)(2)] center dot 8.8H(2)O and [Cu(4-Mecdoa)(phen)(2)] center dot 13H(2)O (phen=1,10-phenanthroline)'. Journal of Inorganic Biochemistry, 101 :1108-1119. [DOI][Full-Text]
2007
Thati B.; Noble A.; Creaven B.; Walsh M.; McCann M.; Kavanagh K.; Devereux M.; Egan D. (2007) 'In vitro anti-tumour and cyto-selective effects of coumarin-3-carboxylic acid and three of its hydroxylated derivatives, along with their silver-based complexes, using human epithelial carcinoma cell lines'. Cancer Letters, 248 (2):321-331. [DOI]
2007
Thati B.; Noble A.; Creaven B.; Walsh M.; McCann M.; Kavanagh K.; Devereux M.; Egan D. (2007) 'A study of the role of apoptotic cell death and cell cycle events mediating the mechanism of action of 6-hydroxycoumarin-3-carboxylatosilver in human malignant hepatic cells'. Cancer Letters, 250 (1):128-139. [DOI]
2006
Reeves, EP; Nagl, M; O'Keeffe, J; Kelly, J; Kavanagh, K (2006) 'Effect of N-chlorotaurine on Aspergillus, with particular reference to destruction of secreted gliotoxin'. Journal of Medical Microbiology, 55 :913-918. [DOI][Full-Text]
2006
Renwick, J; Daly, P; Reeves, EP; Kavanagh, K (2006) 'Susceptibility of larvae of Galleria mellonella to infection by Aspergillus fumigatus is dependent upon stage of conidial germination'. Mycopathologia, 161 :377-384. [DOI][Full-Text]
2006
Reeves, EP; Reiber, K; Neville, C; Scheibner, O; Kavanagh, K; Doyle, S (2006) 'A nonribosomal peptide synthetase (Pes1) confers protection against oxidative stress in Aspergillus fumigatus'. FEBS Journal, 273 :3038-3053. [DOI][Full-Text]
2006
Bergin, D; Murphy, L; Keenan, J; Clynes, M; Kavanagh, K (2006) 'Pre-exposure to yeast protects larvae of Galleria mellonella from a subsequent lethal infection by Candida albicans and is mediated by the increased expression of antimicrobial peptides'. Microbes and Infection, 8 :2105-2112. [DOI][Full-Text]
2006
Creaven, BS; Egan, DA; Kavanagh, K; McCann, M; Noble, A; Thati, B; Walsh, M (2006) 'Synthesis, characterization and antimicrobial activity of a series of substituted coumarin-3-carboxylatosilver(I) complexes'. Inorganica Chimica Acta, 359 :3976-3984. [DOI][Full-Text]
2006
Rowan, R; Tallon, T; Sheahan, AM; Curran, R; McCann, M; Kavanagh, K; Devereux, M; McKee, V (2006) ''Silver bullets' in antimicrobial chemotherapy: Synthesis, characterisation and biological screening of some new Ag(I)-containing imidazole complexes'. Polyhedron, 25 :1771-1778. [DOI][Full-Text]
2006
Carberry, S; Neville, CM; Kavanagh, KA; Doyle, S (2006) 'Analysis of major intracellular proteins of Aspergillus fumigatus by MALDI mass spectrometry: Identification and characterisation of an elongation factor 1B protein with glutathione transferase activity'. Biochemical and Biophysical Research Communications, 341 :1096-1104. [DOI][Full-Text]
2005
Creaven B.; Egan D.; Kavanagh K.; McCann M.; Mahon M.; Noble A.; Thati B.; Walsh M. (2005) 'Synthesis and antimicrobial activity of copper(II) and silver(I) complexes of hydroxynitrocoumarins: X-ray crystal structures of [Cu(hnc) 2(H2O)2] · 2H2O and [Ag(hnc)] (hncH = 4-hydroxy-3-nitro-2H-chromen-2-one)'. Polyhedron, 24 (8):949-957. [DOI][Full-Text]
2005
Neville, C; Murphy, A; Kavanagh, K; Doyle, S (2005) 'A 4 '-phosphopantetheinyl transferase mediates non-ribosomal peptide synthetase activation in Aspergillus fumigatus'. ChemBioChem, 6 :679-685. [DOI][Full-Text]
2005
Bergin, D; Reeves, EP; Renwick, J; Wientjes, FB; Kavanagh, K (2005) 'Superoxide production in Galleria mellonella hemocytes: Identification of proteins homologous to the NADPH oxidase complex of human neutrophils'. Infection and Immunity, 73 :4161-4170. [DOI][Full-Text]
2005
Burns, C; Geraghty, R; Neville, C; Murphy, A; Kavanagh, K; Doyle, S (2005) 'Identification, cloning, and functional expression of three glutathione transferase genes from Aspergillus fumigatus'. Fungal Genetics and Biology, 42 :319-327. [DOI][Full-Text]
2005
Creaven, BS; Egan, DA; Kavanagh, K; McCann, M; Mahon, M; Noble, A; Thati, B; Walsh, M (2005) 'Synthesis and antimicrobial activity of copper(II) and silver(I) complexes of hydroxynitrocoumarins: X-ray crystal structures of [Cu(hnc)(2)(H2O)(2)] center dot 2H(2)O and [Ag(hnc)] (hncH=4-hydroxy-3-nitro-2H-chromen-2-one)'. Polyhedron, 24 :949-957. [DOI][Full-Text]
2005
Reiber, K; Reeves, EP; Neville, CM; Winkler, R; Gebhardt, P; Kavanagh, K; Doyle, S (2005) 'The expression of selected non-ribosornal peptide synthetases in Aspergillus fumigatus is controlled by the availability of free iron'. Fems Microbiology Letters, 248 :83-91. [DOI][Full-Text]
2005
Reiber K.; Reeves E.; Neville C.; Winkler R.; Gebhardt P.; Kavanagh K.; Doyle S. (2005) 'The expression of selected non-ribosomal peptide synthetases in Aspergillus fumigatus is controlled by the availability of free iron'. Fems Microbiology Letters, 248 (1):83-91. [DOI][Full-Text]
2004
Abuskhuna, S; Briody, J; McCann, M; Devereux, M; Kavanagh, K; Fontecha, JB; McKee, V (2004) 'Synthesis, structure and anti-fungal activity of dimeric Ag(I) complexes containing bis-imidazole ligands'. Polyhedron, 23 :1249-1255. [DOI][Full-Text]
2004
Devereux M.; McCann M.; Shea D.; Kelly R.; Egan D.; Deegan C.; Kavanagh K.; McKee V.; Finn G. (2004) 'Synthesis, antimicrobial activity and chemotherapeutic potential of inorganic derivatives of 2-(4′-thiazolyl)benzimidazole{thiabendazole}: X-ray crystal structures of [Cu(TBZH)2Cl]Cl·H 2O·EtOH and TBZH2NO3 (TBZH=thiabendazole)'. Journal of Inorganic Biochemistry, 98 (6):1023-1031. [DOI][Full-Text]
2004
Reeves, EP; Murphy, T; Daly, P; Kavanagh, K (2004) 'Amphotericin B enhances the synthesis and release of the immunosuppressive agent gliotoxin from the pulmonary pathogen Aspergillus fumigatus'. Journal of Medical Microbiology, 53 :719-725. [DOI][Full-Text]
2004
Devereux, M; McCann, M; Shea, DO; Kelly, R; Egan, D; Deegan, C; Kavanagh, K; McKee, V; Finn, G (2004) 'Synthesis, antimicrobial activity and chemotherapeutic potential of inorganic derivatives of 2-(4 '-thiazolyl)benzimidazole thiabendazole: X-ray crystal structures of [Cu(TBZH)(2)Cl]C1 center dot H2O center dot. EtOH and TBZH(2)NO(3) (TBZH = thiabendazole)'. Journal of Inorganic Biochemistry, 98 :1023-1031. [DOI][Full-Text]
2004
McCann, M; Coyle, B; McKay, S; McCormack, P; Kavanagh, K; Devereux, M; McKee, V; Kinsella, P; O'Connor, R; Clynes, M (2004) 'Synthesis and X-ray crystal structure of [Ag(phendio)(2)]ClO4 (phendio=1,10-phenanthroline-5,6-dione) and its effects on fungal and mammalian cells'. BioMetals, 17 :635-645. [Full-Text]
2004
Coyle, B; Kinsella, P; McCann, M; Devereux, M; O'Connor, R; Clynes, M; Kavanagh, K (2004) 'Induction of apoptosis in yeast and mammalian cells by exposure to 1,10-phenanthroline metal complexes'. Toxicology in Vitro, 18 :63-70. [DOI][Full-Text]
2004
Eshwika, A; Coyle, B; Devereux, M; McCann, M; Kavanagh, K (2004) 'Metal complexes of 1,10-phenanthroline-5,6-dione alter the susceptibility of the yeast Candida albicans to amphotericin B and miconazole'. BioMetals, 17 :415-422. [Full-Text]
2004
Reeves, EP; Messina, CGM; Doyle, S; Kavanagh, K (2004) 'Correlation between gliotoxin production and virulence of Aspergillus fumigatus in Galleria mellonella'. Mycopathologia, 158 :73-79. [Full-Text]
2004
Fox, M; Gray, G; Kavanagh, K; Lewis, C; Doyle, S (2004) 'Detection of Aspergillus fumigatus mycotoxins: immunogen synthesis and immunoassay development'. Journal of Microbiological Methods, 56 :221-230. [DOI][Full-Text]
2004
Coyle, B; McCann, M; Kavanagh, K; Devereux, M; McKee, V; Kayal, N; Egan, D; Deegan, C; Finn, GJ (2004) 'Synthesis, X-ray crystal structure, anti-fungal and anti-cancer activity of [Ag-2(NH3)(2)(salH)(2)] (salH(2)= salicylic acid)'. Journal of Inorganic Biochemistry, 98 :1361-1366. [DOI][Full-Text]
2003
O'Keeffe, J; Doyle, S; Kavanagh, K (2003) 'Exposure of the yeast Candida albicans to the anti-neoplastic agent adriamycin increases the tolerance to amphotericin B'. Journal of Pharmacy and Pharmacology, 55 :1629-1633. [DOI][Full-Text]
2003
Geraghty, P; Kavanagh, K (2003) 'Disruption of mitochondrial function in Candida albicans leads to reduced cellular ergosterol levels and elevated growth in the presence of amphotericin B'. Archives of Microbiology, 179 :295-300. [DOI][Full-Text]
2003
Deegan, O; Walshe, K; Kavanagh, K; Doyle, S (2003) 'Quantitative detection of C-reactive protein using phosphocholine-labelled enzyme or microspheres'. Analytical Biochemistry, 312 :175-181. [Full-Text]
2003
Geraghty, P; Kavanagh, K (2003) 'Erythromycin, an inhibitor of mitoribosomal protein biosynthesis, alters the amphotericin B susceptibility of Candida albicans'. Journal of Pharmacy and Pharmacology, 55 :179-184. [DOI][Full-Text]
2003
Coyle, B; Kavanagh, K; McCann, M; Devereux, M; Geraghty, M (2003) 'Mode of anti-fungal activity of 1,10-phenanthroline and its Cu(II), Mn(II) and Ag(I) complexes'. BioMetals, 16 :321-329. [Full-Text]
2003
Ellabib, MS; Refaai, A; Khalifa, Z; Kavanagh, K (2003) 'Isolation and identification of Madurella mycetomatis from two cases of black grain mycetoma in Libya'. Mycoses, 46 :339-341. [Full-Text]
2003
McCann, M; Coyle, B; Briody, J; Bass, F; O'Gorman, N; Devereux, M; Kavanagh, K; McKee, V (2003) 'Synthesis and antimicrobial activity of (Z)-3-(1H-imidazol-1-yl)-2-phenylpropenenitrile and its metal complexes: X-ray crystal structures of the Zn(II) and Ag(I) complexes'. Polyhedron, 22 :1595-1601. [DOI][Full-Text]
2003
Bergin, D; Brennan, M; Kavanagh, K (2003) 'Fluctuations in haemocyte density and microbial load may be used as indicators of fungal pathogenicity in larvae of Galleria mellonella'. Microbes and Infection, 5 :1389-1395. [DOI][Full-Text]
2002
Ellabib, MS; Agaj, M; Khalifa, Z; Kavanagh, K (2002) 'Yeasts of the genus Candida are the dominant cause of onychomycosis in Libyan women but not men: results of a 2-year surveillance study'. British Journal of Dermatology, 146 :1038-1041. [Full-Text]
2002
Ellabib, MS; Khalifa, Z; Kavanagh, K (2002) 'Dermatophytes and other fungi associated with skin mycoses in Tripoli, Libya'. Mycoses, 45 :101-104. [Full-Text]
2002
Daly, P; Kavanagh, K (2002) 'Immobilization of Aspergillus fumigatus colonies in a soft agar matrix allows visualization of A549 cell detachment and death'. Medical Mycology, 40 :27-33. [Full-Text]
2002
Brennan, M; Thomas, DY; Whiteway, M; Kavanagh, K (2002) 'Correlation between virulence of Candida albicans mutants in mice and Galleria mellonella larvae'. FEMS Immunology and Medical Microbiology, 34 :153-157. [Full-Text]
2002
Ellabib, MS; Agaj, M; Khalifa, Z; Kavanagh, K (2002) 'Trichophyton violaceum is the dominant cause of tinea capitis in children in Tripoli, Libya: Results of a two year survey'. Mycopathologia, 153 :145-147. [Full-Text]
2001
Ennis, O; Corcoran, A; Kavanagh, K; Mahon, BP; Doyle, S (2001) 'Baculovirus expression of parvovirus B19 (B19V) NS1: utility in confirming recent infection'. Journal of Clinical Virology, 22 :55-60. [Full-Text]
2001
Daly P.; Kavanagh K. (2001) 'Pulmonary aspergillosis: Clinical presentation, diagnosis and therapy'. British Journal of Biomedical Science, 58 (3):197-205. [Full-Text]
2001
Murphy A.; Kavanagh K. (2001) 'Adherence of clinical isolates of Saccharomyces cerevisiae to buccal epithelial cells'. Medical Mycology, 39 (1):123-127. [Full-Text]
2001
Murphy, AR; Kavanagh, KA (2001) 'Adherence of clinical isolated of Saccharomyces cerevisiae to buccal epithelial cells'. Medical Mycology, 39 :123-127. [Full-Text]
2000
Cotter, G; Doyle, S; Kavanagh, K (2000) 'Development of an insect model for the in vivo pathogenicity testing of yeasts'. FEMS Immunology and Medical Microbiology, 27 :163-169. [Full-Text]
2000
Cotter G.; Kavanagh K. (2000) 'Adherence mechanisms of Candida albicans'. British Journal of Biomedical Science, 57 (3):241-249. [Full-Text]
1999
Al-Rawi, N; Kavanagh, K (1999) 'Characterisation of yeasts implicated in vulvovaginal candidosis in Irish women'. British Journal of Biomedical Science, 56 :99-104.
1999
Daly, P; Verhaegen, S; Clynes, M; Kavanagh, K (1999) 'Culture filtrates of Aspergillus fumigatus induce different modes of cell death in human cancer cell lines'. Mycopathologia, 146 :67-74. [Full-Text]
1998
Cotter, G; Weedle, R; Kavanagh, K (1998) 'Monoclonal antibodies directed against extracellular matrix proteins reduce the adherence of Candida albicans to HEp-2 cells'. Mycopathologia, 141 :137-142. [Full-Text]
1998
Al-Rawi, N; Kavanagh, K (1998) 'A rapid method for the extraction of whole cell proteins from Candida species'. Journal of Microbiological Methods, 34 :107-112. [Full-Text]
1997
Cotter, G; Verhaegen, S; Clynes, M; Kavanagh, K (1997) 'Membrane changes associated with the early stages of apoptosis in HEp-2 cells decrease susceptibility adherence by Candida albicans'. Journal of Medical and Veterinary Mycology, 35 :219-224. [Full-Text]
1996
Kavanagh, K; Whittaker, PA (1996) 'Application of protoplast fusion to the nonconventional yeast'. Enzyme and Microbial Technology, 18 :45-51. [Full-Text]
1994
KAVANAGH, K; WHITTAKER, PA (1994) 'APPLICATION OF THE MELLE-BOINOT PROCESS TO THE FERMENTATION OF XYLOSE BY PACHYSOLEN-TANNOPHILUS'. Applied Microbiology and Biotechnology, 42 :28-31.
1994
LAW, C; KAVANAGH, K; WHITTAKER, P (1994) 'ANALYSIS OF HYBRIDS OF CANDIDA-ALBICANS FORMED BY PROTOPLAST FUSION'. Fems Microbiology Letters, 115 :77-82. [Full-Text]
1992
KAVANAGH, K; WEEDLE, R; GHANNOUM, M; WHITTAKER, P (1992) 'A NOVEL TECHNIQUE FOR STUDYING THE ADHERENCE OF CANDIDA-ALBICANS TO HEP-2 CELLS'. Journal of Microbiological Methods, 16 :39-46.
1992
REEVES, E; KAVANAGH, K; WHITTAKER, PA (1992) 'MULTIPLE TRANSFORMATION OF SACCHAROMYCES-CEREVISIAE BY PROTOPLAST FUSION'. Fems Microbiology Letters, 99 :193-197. [Full-Text]
1991
KAVANAGH, K; WALSH, M; WHITTAKER, PA (1991) 'ENHANCED INTRASPECIFIC PROTOPLAST FUSION IN YEAST'. Fems Microbiology Letters, 81 :283-286. [Full-Text]
1991
KAVANAGH, K; WHITTAKER, PA (1991) 'FUNCELASE - AN EFFICIENT PREPARATION FOR THE ISOLATION OF REVERSION COMPETENT PROTOPLASTS FROM YEASTS'. Biotechnology Techniques, 5 :313-316. [Full-Text]
1990
KAVANAGH, K; WHITTAKER, PA (1990) 'FORMATION OF SPHEROPLASTS AND PROTOPLASTS IN THE XYLOSE-FERMENTING YEAST PACHYSOLEN-TANNOPHILUS'. Biotechnology and Applied Biochemistry, 12 :57-62.
2012
A. Eshwika, J. Kelly, J. P. Fallon and K. Kavanagh (2012) 'Exposure of Aspergillus fumigatus to caspofungin results in the release, and de novo biosynthesis, of gliotoxin'. Medical Mycology, 50 . [Full-Text]
2005
Neville, C., Murphy, A., Kavanagh, K. and Doyle S. (2005) 'A 4’-phosphopantetheinyl transferase mediates non-ribosomal peptide synthetase activation in Aspergillus fumigatus'. ChemBioChem, 6 :679-685. [Full-Text]
2004
Eshwika, A., Coyle, B, Devereux, M, McCann, M. and Kavanagh, K. (2004) 'Metal-complexes of 1, 10 phenanthroline-5,6-dione alter the susceptibility of the yeast Candida albicans to Amphotericin B and Miconazole'. BioMetals, 17 :415-422. [Full-Text]
2023
Piatek, M.; O’Beirne, C.; Beato, Z.; Tacke, M.; Kavanagh, K. (2023) 'Pseudomonas aeruginosa and Staphylococcus aureus Display Differential Proteomic Responses to the Silver(I) Compound, SBC3'. Antibiotics, 12 . [Link][DOI]
2023
Curtis, A.; Ryan, M.; Kavanagh, K. (2023) 'Exposure of Aspergillus fumigatus to Klebsiella pneumoniae Culture Filtrate Inhibits Growth and Stimulates Gliotoxin Production'. Journal Of Fungi, 9 . [Link][DOI]
2023
More O'Ferrall, L.; Piatek, M.; Twamley, B.; Kavanagh, K.; O'Connor, C.; Griffith, D.M. (2023) 'Synthesis, characterisation and antibacterial activity of novel Ga(iii) polypyridyl catecholate complexes'. Dalton Transactions, . [Link][DOI][Full-Text]
2022
Piatek M.; O'Beirne C.; Beato Z.; Tacke M.; Kavanagh K. (2022) 'Exposure of Candida parapsilosis to the silver(I) compound SBC3 induces alterations in the proteome and reduced virulence'. Metallomics, 14 (8). [DOI][Full-Text]
2022
O’Shaughnessy M.; Piatek M.; McCarron P.; McCann M.; Devereux M.; Kavanagh K.; Howe O. (2022) 'In Vivo Activity ofMetal Complexes Containing 1,10-Phenanthroline and 3,6,9-Trioxaundecanedioate Ligands against Pseudomonas aeruginosa Infection in Galleria mellonella Larvae'. Biomedicines, 10 (2). [DOI]
2022
Clarke J.; Grogan H.; Fitzpatrick D.; Kavanagh K. (2022) 'Characterising the proteomic response of mushroom pathogen Lecanicillium fungicola to Bacillus velezensis QST 713 and Kos biocontrol agents'. European Journal of Plant Pathology, . [DOI][Full-Text]
2022
Ahmed, M; Ward, S; McCann, M; Kavanagh, K; Heaney, F; Devereux, M; Twamley, B; Rooney, D (2022) 'Synthesis and characterisation of phenanthroline-oxazine ligands and their Ag(I), Mn(II) and Cu(II) complexes and their evaluation as antibacterial agents'. BioMetals, . [DOI][Full-Text]
2022
Irfan I.; Ali A.; Reddi B.; Khan M.A.; Hasan P.; Ahmed S.; Uddin A.; Piatek M.; Kavanagh K.; Haque Q.M.R.; Singh S.; Addlagatta A.; Abid M. (2022) 'Design, Synthesis and Mechanistic Studies of Novel Isatin-Pyrazole Hydrazone Conjugates as Selective and Potent Bacterial MetAP Inhibitors'. Journal of Antibiotics, 11 (8). [DOI][Full-Text]
2022
Ward R.; Coffey M.; Kavanagh K. (2022) 'Proteomic characterisation of the summer–winter transition in Apis mellifera'. Apidologie, 53 (4). [DOI]
Dib K.; El Banna A.; Radulescu C.; Lopez Campos G.; Sheehan G.; Kavanagh K. (2022) 'Histamine Produced by Gram-Negative Bacteria Impairs Neutrophil's Antimicrobial Response by Engaging the Histamine 2 Receptor'. Journal of Innate Immunity, . [DOI][Full-Text]
2022
Ward, R; Coffey, MF; Kavanagh, K (2022) 'Exposure of Apis mellifera to anti-Varroa destructor formic acid treatment induces significant proteomic alterations'. Journal of Apicultural Research, . [DOI][Full-Text]
2022
Margalit A; Sheehan D; Carolan JC; Kavanagh K; (2022) 'Exposure to the Pseudomonas aeruginosa secretome alters the proteome and secondary metabolite production of Aspergillus fumigatus'. Microbiology - Society for General Microbiology, 168 (3). [DOI][Full-Text]
2022
Ward R.; Coffey M.; Kavanagh K. (2022) 'Proteomic analysis of summer and winter Apis mellifera workers shows reduced protein abundance in winter samples'. Journal of Insect Physiology, 139 . [DOI]
2021
Martin H.; Goyard D.; Margalit A.; Doherty K.; Renaudet O.; Kavanagh K.; Velasco-Torrijos T. (2021) 'Multivalent Presentations of Glycomimetic Inhibitor of the Adhesion of Fungal Pathogen Candida albicans to Human Buccal Epithelial Cells'. Bioconjugate Chemistry, . [DOI][Full-Text]
2021
Gallagher, L; Smith, A; Kavanagh, K; Devereux, M; Colleran, J; Breslin, C.B; Richards, K; McCann, M; Rooney, AD (2021) 'Preparation and Antimicrobial Properties of Alginate and Serum Albumin/Glutaraldehyde Hydrogels Impregnated with Silver(I) Ions'. Chemistry, 3 (2):672-686. [Full-Text]
2021
Piatek, M; Sheehan, G; Kavanagh, K (2021) 'Galleria mellonella: The Versatile Host for Drug Discovery, In Vivo Toxicity Testing and Characterising Host-Pathogen Interactions'. Journal of Antibiotics, 10 . [DOI][Full-Text]
2021
Asai, M; Sheehan, G; Li, YW; Robertson, BD; Kavanagh, K; Langford, PR; Newton, SM (2021) 'Innate Immune Responses of Galleria mellonella to Mycobacterium bovis BCG Challenge Identified Using Proteomic and Molecular Approaches'. Frontiers in Cellular and Infection Microbiology, 11 . [DOI][Full-Text]
2021
Ali A.; Hasan P.; Irfan M.; Uddin A.; Khan A.; Saraswat J.; Maguire R.; Kavanagh K.; Patel R.; Joshi M.C.; Azam A.; Mohsin M.; Haque Q.M.R.; Abid M. (2021) 'Development of Oxadiazole-Sulfonamide-Based Compounds as Potential Antibacterial Agents'. Acs Omega, . [DOI][Full-Text]
2021
Clarke J.; Grogan H.; Fitzpatrick D.; Kavanagh K. (2021) 'Analysis of the effect of Bacillus velezensis culture filtrate on the growth and proteome of Cladobotryum mycophilum'. Fungal Biology, . [DOI][Full-Text]
2021
Evans A.; Kavanagh K.A. (2021) 'Evaluation of metal-based antimicrobial compounds for the treatment of bacterial pathogens'. Journal of Medical Microbiology, 70 (5). [DOI][Full-Text]
2021
Sheehan G.; Margalit A.; Sheehan D.; Kavanagh K. (2021) 'Proteomic profiling of bacterial and fungal induced immune priming in Galleria mellonella larvae'. Journal of Insect Physiology, 131 . [DOI][Full-Text]
2021
Margalit, Anatte,Carolan, James C,Kavanagh, Kevin (2021) 'Bacterial Interactions with Aspergillus fumigatus in the Immunocompromised Lung'. 9 (2). [Link][Full-Text]
2021
Ude Z.; Flothkötter N.; Sheehan G.; Brennan M.; Kavanagh K.; Marmion C.J. (2021) 'Multi-targeted metallo-ciprofloxacin derivatives rationally designed and developed to overcome antimicrobial resistance'. International Journal of Antimicrobial Agents, . [DOI][Full-Text]
2021
Martin H.; Masterson H.; Kavanagh K.; Velasco-Torrijos T. (2021) 'The synthesis and evaluation of multivalent glycopeptoids as inhibitors of the adhesion of candida albicans'. Pathogens, 10 (5). [DOI][Full-Text]
2021
O'Beirne C.; Piatek M.E.; Fossen J.; Müller-Bunz H.; Andes D.R.; Kavanagh K.; Patil S.A.; Baumann M.; Tacke M. (2021) 'Continuous flow synthesis and antimicrobial evaluation of NHC* silver carboxylate derivatives of SBC3 in vitro and in vivo'. Metallomics, 13 (2). [DOI][Full-Text]
2021
Lathwal, A; Ali, A; Uddin, A; Khan, NS; Sheehan, G; Kavanagh, K; Haq, QMR; Abid, M; Nath, M (2021) 'Assessment of Dihydro[1,3]oxazine-Fused Isoflavone and 4-Thionoisoflavone Hybrids as Antibacterials'. Chemistryselect, 6 :7505-7513. [DOI][Full-Text]
2021
Kosanovic, D; Dyas, M; Grogan, H; Kavanagh, K (2021) 'Differential proteomic response of Agaricus bisporus and Trichoderma aggressivum f. europaeum to Bacillus velezensis supernatant'. European Journal of Plant Pathology, . [DOI][Full-Text]
2020
Piatek, M; Griffith, DM; Kavanagh, K (2020) 'Quantitative proteomic reveals gallium maltolate induces an iron-limited stress response and reduced quorum-sensing in Pseudomonas aeruginosa'. Journal of Biological Inorganic Chemistry, . [DOI]
2020
Martin, H; Somers, T; Dwyer, M; Robson, R; Pfeffer, FM; Bjornsson, R; Kramer, T; Kavanagh, K; Velasco-Torrijos, T (2020) 'Scaffold diversity for enhanced activity of glycosylated inhibitors of fungal adhesion'. Rsc Medicinal Chemistry, 11 . [DOI]
Dr Adrian P Kavanagh . .
2023
Curtis, A.; Walshe, K.; Kavanagh, K. (2023) 'Prolonged Subculturing of Aspergillus fumigatus on Galleria Extract Agar Results in Altered Virulence and Sensitivity to Antifungal Agents'. Cells, 12 . [Link][DOI]
2019
Doyle A.A.; Krämer T.; Kavanagh K.; Stephens J.C. (2019) 'Cinnamaldehydes: Synthesis, antibacterial evaluation, and the effect of molecular structure on antibacterial activity'. Results in Chemistry, 1 . [DOI]
2016
McMahon, F; Banville, N; Bergin, D; Smedman, C; Paulie, S; Reeves, E; Kavanagh, K. (2016) 'Activation of neutrophils via IP3 pathway following exposure to Demodex associated bacterial proteins'. Journal of Inflammation, 5 . [DOI][Full-Text]
2015
Dunbar J.; Zarelli M.; Martin S.; Gandola R.; Kavanagh K.; Walsh F.; Rivas J. (2015) 'Trunk vertebrae osteomyelitis in a spectacled caiman (Caiman crocodilus)'. Herpetological Bulletin, (134):15-18. [Full-Text]
2015
Maurer E, Browne N, Surlis C, Jukic E, Moser P, Kavanagh K, Lass-Flörl C and Binder U. (2015) 'Galleria mellonella as a host model to study Aspergillus terreus virulence and amphotericin B treatment'. Virulence . [Full-Text]
2015
Browne, N, Surlis, C., Maher A, Gallagher C, Carolan, J., Clynes M, Kavanagh K. (2015) 'Prolonged pre-incubation reduces the immune response of Galleria mellonella larvae to bacterial and fungal infection'. Virulence 6 :1-8.
2013
Browne N and Kavanagh K (2013) 'Developing the potential of using Galleria mellonella larvae as models for studying brain infection by Listeria monocytogenes'. Virulence 4 :271-272. [Full-Text]
2013
Dolan, N., McGinley, J. Stephens, J., Kavanagh, K., Hurley, D., Maher, N (2013) 'Synthesis, characterisation and antimicrobial studies of organotin(IV) complexes with 1,10-phenanthroline derivatives'. Inorganica Chimica Acta, 409 :276-284. [Full-Text]
2013
Thati, B; Noble, A; Creaven, BS; Walsh, M; McCann, M; Kavanagh, K; Devereux, M; Egan, DA (2013) 'In vitro anti-tumour and cyto-selective effects of coumarin-3-carboxylic acid and three of its hydroxylated derivatives, along with their silver-based complexes, using human epithelial carcinoma cell lines (Retraction of vol 248, pg 321, 2007)'. Cancer Letters, 338 :330-330.
2013
Browne N., Heelan M, Kavanagh K. (2013) 'An analysis of the structural and functional similarities of insect hemocytes and mammalian phagocytes'. Virulence 4 :1-7. [Full-Text]
2013
OKeeffe, G., Jchl, C., Kavanagh, K. and Doyle S. (2013) 'Extensive Proteomic Remodelling is Induced by Eukaryotic Translation Elongation Factor 1Bγ (ElfA) Deletion in Aspergillus fumigatus'. Protein Science, 22 :1612-1622. [Full-Text]
2012
Kellett A., O’Connor M., McCann M., Howe O., Casey A, McCarron P., Kavanagh K., McNamara M., Kennedy S., May DD, Skell PS, O’Shea D and Devereux M. (2012) 'Water-soluble bis(1,10-phenanthroline) octanedioate Cu2+ and Mn2+ complexes with unprecedented nano and picomolar in vitro cytotoxicity: promising leads for chemotherapeutic drug development'. Medicinal Chemistry Research, 2 :579-583. [DOI][Full-Text]
2012
O’Hanlon K., Gallagher L., Schrettl M., Jochl C., Kavanagh K., Larsen TO, and Doyle S. (2012) 'Non-Ribosomal Peptide Synthetases pesL and pes1 are essential for Fumigaclavine C production in Aspergillus fumigatus'. Applied And Environmental Microbiology, 78 :3166-3176. [Full-Text]
2012
N. O’Reilly, N. Menezes, and K. Kavanagh (2012) 'Positive correlation between serum immuno-reactivity to Demodex-associated Bacillus proteins and Erythematotelangiectic Rosacea'. British Journal of Dermatology, 166 . [Full-Text]
2012
O’Reilly N., Gallagher C., Reddy Katikireddy K., Clynes M., O’Sullivan F. and Kavanagh K. (2012) 'Demodex-associated Bacillus proteins induce an aberrant wound healing response in a corneal epithelial cell line (hTCEpi): possible implications for corneal ulcer formation in Ocular rosacea'. Investigative Ophthalmology & Visual Science, 53 :3250-3259. [Full-Text]
2012
Dr Conrad Brunstrom
Dr Declan Kavanagh (2012) 'Arthur Murphy and Florida Peat: The Grays Inn Journal and versions of the apolitical'. Eighteenth-Century Ireland, 27 . [Full-Text]
2012
Fallon J, Kelly J, Kavanagh K. (2012) 'Galleria mellonella as a Model for Fungal Pathogenicity Testing'. Methods in Molecular Biology, 845 :469-485. [Full-Text]
Whelan, E. T.; Ray, T. P. search by orcid; Comeron, F.; Bacciotti, F. search by orcid; Kavanagh, P. J. (2012) 'Spatially Resolved Observations of the Bipolar Optical Outflow from the Brown Dwarf 2MASS J12073347-3932540'. Astrophysical Journal, .
2012
Kavanagh, P. J.; Sasaki, M.; Points, S. D. (2012) 'XMM-Newton view of the N 206 superbubble in the Large Magellanic Cloud'. Astronomy and Astrophysics, .
2012
S. Jarmuda, N. O'Reilly, ,R. Żaba, O. Jakubowicz, A. Szkaradkiewicz and K. Kavanagh (2012) 'The potential role of Demodex folliculorum mites and bacteria in the induction of rosacea'. Journal of Medical Microbiology, 61 :1504-1510. [Full-Text]
2011
Kelly J. and Kavanagh K. (2011) 'Caspofungin primes the immune response of larvae of Galleria mellonella and induces a non-specific antimicrobial response'. Journal of Medical Microbiology, 60 :189-196. [Full-Text]
2011
Davis, C., Carberry S., Schrettl, M., Singh I., Stephens, J., Barry, S., Kavanagh, K., Challis, Broughan D., Doyle, S. (2011) 'The Role of Glutathione S-transferase GliG in Gliotoxin Biosynthesis in Aspergillus fumigatus'. Chemistry and Biology, 28 . [Full-Text]
2011
Fallon JP, Reeves E.P. and Kavanagh K. (2011) 'The Aspergillus fumigatus toxin Fumagillin suppresses the immune response of Galleria mellonella larvae by inhibiting the action of haemocytes'. 157 :1481-1488. [Full-Text]
2011
Davis, Carol; Carberry, Stephen; Schrettl, Markus; Singh, Ishwar; Stephens, John C.; Barry, Sarah M.; Kavanagh, Kevin; Challis, Gregory L.; Brougham, Dermot; Doyle, Sean (2011) 'The Role of Glutathione S-Transferase GliG in Gliotoxin Biosynthesis in Aspergillus fumigatus'. Chemistry and Biology, 18 :542-552. [DOI][Full-Text]
2011
Davis, C., Carberry, S., Schrettl, M., Singh, I., Stephens, J.C., Barry, S. M., Kavanagh, K., Challis, G.L., Brougham, D., and Doyle, S. (2011) 'The Role of Glutathione S-Transferase GliG
in Gliotoxin Biosynthesis in Aspergillus fumigatus'. Chemistry and Biology, 18 :542-552. [DOI][Full-Text]
2011
Costello A, Herbert G., Fabunmi, L. Schaffer K.E., Kavanagh K, Caraher E, Callaghan M, and McClean S (2011) 'Virulence of emerging respiratory pathogen, genus Pandoraea, in vivo and its interactions with lung epithelial cells'. Journal of Medical Microbiology, 60 :289-299. [Full-Text]
2010
Schrettl, M., Carberry, S., Kavanagh, K., Haas, H., Jones G.W., O'Brien J., Stephens J., Fenelon, O., Nolan, A. and Doyle, S. (2010) 'Self-Protection against Gliotoxin—A Component of the Gliotoxin Biosynthetic Cluster, GliT, Completely Protects Aspergillus fumigatus Against Exogenous Gliotoxin'. PLoS Pathogens, 6 . [DOI][Full-Text]
2010
Schrettl, M., Carberry, S., Kavanagh, K., Haas, H., Jones G.W., O'Brien J., Stephens J., Fenelon, O., Nolan, A. and Doyle, S. (2010) 'Gliotoxin Biosynthetic Cluster, GliT, Completely Protects Aspergillus fumigatus Against Exogenous Gliotoxin'. PLoS Pathogens, 6 . [DOI][Full-Text]
2010
Creaven, B.S., Duff, B., Egan, D.A., Kavanagh, K., Rosair, G., Thangella, V.R., Walsh, M. (2010) 'Anticancer and Antifungal Activity of Copper(II) complexes of Quinolin-2(1H)-one-derived Schiff Bases’'. 363 :4048-4058. [Full-Text]
2008
Mowlds, P. and K. Kavanagh (2008) 'Effect of pre-incubation temperature on susceptibility of Galleria mellonella to infection by Candida albicans'. Mycopathologia, 165 :5-12. [Full-Text]
2007
Creaven,B., Egan D. Karcz, D., Kavanagh,K ., McCann, M., Mahon, M. Noble, A., Thati, B., Walsh. M. (2007) 'Synthesis, characterisation, antimicrobial and in vitro anticancer activity of copper(II) and manganese(II) complexes of 2-(2-oxo-2H-chromen-6yloxy-7carboxymethyloxy)acetic acid (coumarin-6,7-dioxyacteic acid, cdoaH2) and 2-(2-oxo-2H-chromen-4-methyl-6yloxy-7carboxymethyloxy)acetic acid, (4-methylcoumarin-6,7-dioxyacteic acid, 4-MecdoaH2): X-ray Crystal structures of the phenanthroline adducts [Cu(cdoa)(phen)2]·8.8H2O and [Cu(4-mecdoa)(phen)2]·13H2O'. 101 :1108-1119.
2007
Thati, B., Kavanagh, K. and Egan, D. (2007) 'Apoptotic cell death: A possible key event in mediating the in vitro anti-proliferative effect of a novel copper(II) complex, [Cu(4-Mecdoa)(phen)2] (phen = phenanthroline, 4-Mecdoa = 4-methylcoumarin-6,7-dioxactetate), in human malignant cancer cells'. European Journal of Pharmacology, 569 :16-28. [Full-Text]
2007
Renwick, J., Reeves, E.P., Frans B. Wientjes and Kavanagh, K. (2007) 'Translocation of proteins homologous to human neutrophil p47phox and p67phox to the cell membrane in activated hemocytes of Galleria mellonella'. Developmental and Comparative Immunology, 31 :347-359. [Full-Text]
2007
Lacey, N., Delaney, S., Kavanagh, K. and Powell, F.C. (2007) 'Mite related antigens stimulate inflammatory dells in rosacea'. British Journal of Dermatology, 157 :474-481. [Full-Text]
2007
Thati, B., Noble, A., Creaven, B.S., Walsh, M., Kavanagh, K. and Egan, D.A. (2007) 'An in vitro investigation of the induction of apoptosis and modulation of cell cycle events in human cancer cells by bisphenanthroline-coumarin-6,7-dioxacetatocopper(II) complex. '. Chemico-Biological Interactions, 168 :143-158.
2006
Reeves E.P., Nagl, M., O’Keeffe, J.,Kelly, J., and Kavanagh, K (2006) 'The effect of N-chlorotaurine on Aspergillus, with particular reference to the destruction of secreted gliotoxin'. Journal of Medical Microbiology, 55 :913-918. [Full-Text]
2006
Rowan, R, Tallon, T Sheahan, A., Curran, R., McCann, M., Kavanagh, K. Devereux, M. and McKee V. (2006) '‘Silver bullets’ in antimicrobial chemotherapy: synthesis, characterisation and biological screening of some new Ag(I)-containing imidazole complexes'. Polyhedron, 25 :1771-1778. [Full-Text]
2006
Creaven BS, Egan DA, Kavanagh, K. McCann, M., Noble, A Thati, B., Walsh. M. (2006) 'Synthesis, anti-microbial and anti-cancer activity of a series of substituted coumarin-3-carboxylatosilver(I) complexes'. 359 :3976-3984. [Full-Text]
2006
Bergin, D., Murphy, L Keenan, J., Clynes, M. and Kavanagh, K. (2006) 'Pre-exposure to yeast protects larvae of Galleria mellonella from a subsequent lethal infection by Candida albicans and is mediated by the increased expression of antimicrobial peptides'. Microbes and Infection, 8 :2105-2112. [Full-Text]
2005
Creaven, BS., Egan, DA., Kavanagh, K., McCann, M., Mahon, M., Noble, A., Thati, B. and Walsh. M (2005) 'Synthesis and Antimicrobial Activity of Copper(II) and Silver(I) Complexes of Hydoxynitrocoumarins: X-ray crystal structures of [Cu(hnc)2(H2O)2]×2H2O and [Ag(hnc)] (hncH = 4-hydroxy-3-nitro-2H-chromen-2-one)'. Polyhedron, 24 :949-957. [Full-Text]
2005
Bergin, D. Reeves, EP, Renwick, J. Wientjes FB. and Kavanagh, K. (2005) 'Superoxide production in haemocytes of Galleria mellonella – identification of proteins homologous to the NADPH oxidase complex of human neutrophils'. Infection and Immunity, 73 :4161-4173. [Full-Text]
2005
B.S. Creaven, D.A. Egan, K. Kavanagh, M. McCann, M. Mahon, A. Noble, B. Thati, M. Walsh (2005) 'Synthesis and Antimicrobial Activity of Copper(II) and Silver(I) Complexes of Hydoxynitrocoumarins: X-ray crystal structures of [Cu(hnc)2(H2O)2]×2H2O and [Ag(hnc)] (hncH = 4-hydroxy-3-nitro-2H-chromen-2-one)'. Polyhedron, 24 :1771-1778. [Full-Text]
2004
Devereux, M., McCann, M., O Shea, D., Kelly , R., Egan,D., C. Deegan C., Kavanagh, K. and McKee, V. (2004) 'Synthesis, antimicrobial activity and chemotherapeutic potential of inorganic derivatives of 2-(4’-thiazolyl)benzimazole {thiabendazole}: X-ray crystal structures of [Cu(TBZH)2Cl]Cl.H2O.EtOH and TBZH2NO3 (TBZH = thiabendazole)'. 98 :1023-1031. [Full-Text]
2004
A. Abuskhuna, J. M. Briody, M. McCann, M. Devereux, K. Kavanagh, J.B. Fontecha, V. McKee (2004) 'Synthesis, structure and anti-fungal activity of dimeric Ag(1) complexes containing bis-imidazole ligands'. Polyhedron, 23 :1249-1255. [Full-Text]
2004
B. Coyle, M. McCann, K. Kavanagh, M. Devereux, V. McKee, N. Kayal, D. Egan, C. Deegan, G. Finn (2004) 'Synthesis, X-ray crystal structure, anti-fungal and anti-cancer activity of [Ag2 (NH3)2(salH)2] (salH2 = Salicylic Acid)'. 98 :1361-1366. [Full-Text]
2004
Kavanagh, K. and Reeves, E.P. (2004) 'Exploiting the potential of Insects for in vivo pathogenicity testing of Microbial pathogens'. FEMS Microbiology Reviews, 28 :101-112. [Full-Text]
2004
Kavanagh, K. and Dowd, S. (2004) 'Histatins: antimicrobial peptides with therapeutic potential'. Journal of Pharmacy and Pharmacology, 56 :285-289. [Full-Text]
2004
Reeves, EP., .Messina, CGM, Doyle, S. and Kavanagh, K. (2004) 'Correlation of Gliotoxin Production and Virulence of Aspergillus fumigatus in Galleria mellonella'. Mycopathologia, 158 :73-79.
2004
McCann, M, Coyle, B, McKay, S, McCormack, P, Devereux, M, Kavanagh, K, McKee, V, Kinsella, P, O'Connor, R. and Clynes, M. (2004) 'Synthesis and X-ray Crystal Structure of [Ag(phendio)2]ClO4 (phendio = 1,10-Phenanthroline-5,6-dione) and its Effects on Fungal and Mammalian Cells'. BioMetals, 17 :635-645. [Full-Text]
2004
Coyle, B, Kinsella, P, McCann, M, Devereux, M, O'Connor, R, Clynes M. and Kavanagh, K. (2004) 'Induction of apoptosis in yeast and mammalian cells by exposure to 1,10 phenanthroline metal complexes'. Toxicology in Vitro, 18 :63-70. [Full-Text]
2003
Bergin, D., Brennan, M., and Kavanagh, K. (2003) 'Fluctuations in haemocyte density and microbial load may be used as indicators of fungal pathogenicity in larvae of Galleria mellonella'. Microbes and Infection, 5 :1389-1395. [Full-Text]
2003
O'Keeffe, J., Doyle, S. and Kavanagh, K. (2003) 'Exposure of the yeast Candida albicans to the anti-neoplastic agent Adriamycin increases the tolerance to Amphotericin B'. Journal of Pharmacy and Pharmacology, 55 :1629-1633. [Full-Text]
2003
Deegan, O., Walshe, K. Kavanagh, K. and Doyle, S. (2003) 'Quantitative detection of C-reactive protein using phosphocholine-labelled enzymes or microspheres'. Analytical Biochemistry, 312 :175-181. [Full-Text]
2003
CoyleB.. KavanaghK., McCann M., Devereux M. and Geraghty M. (2003) 'Mode of anti-fungal activity of 1,10-phenanthroline and its Cu(H), Mn(II) and Ag(I) complexes'. BioMetals, 16 :321-329. [Full-Text]
2002
Ellabib M, Agaj M, Khalifa Z and Kavanagh K (2002) 'Trichophyton violaceum as an important cause of tinea capitis in children in Tripoli (Libya): Results of a two year survey'. Mycopathologia, 153 :145-147. [Full-Text]
2002
Brennan M, Thomas DY, Whiteway M and Kavanagh K (2002) 'Analysis of Candida albicans virulence in Galleria mellonella larvae'. FEMS Immunology and Medical Microbiology, 34 :153-157.
2002
Daly, P.& Kavanagh, K. (2002) 'Immobilisation of Aspergillus fumigatus colonies in a soft agar matrix allows visualisation of A549 cell detachment and death'. Medical Mycology, 40 :27-33.
2002
Ellabib M, Agaj M, Khalifa Z and Kavanagh K (2002) 'Yeasts of the genus Candida are the dominant cause of onychomycosis in Libyan women but not men: Results of a two year surveillance study'. British Journal of Dermatology, 146 :1038-1041. [Full-Text]
1999
Murphy, A. & Kavanagh, K. (1999) 'The emergence of Saccharomyces cerevisiae as a human pathogen: Implications for Biotechnology'. Enzyme and Microbial Technology, 25 :551-557. [Full-Text]
1999
Daly, P., Verhaegen, S., Clynes, M. and Kavanagh, K. (1999) 'Modes of cell death in human cancer cell lines exposed to Aspergillus fumigatus culture filtrates'. Mycopathologia, 146 :67-74. [Full-Text]
1998
Duffy, C., Elliott, C., O'Connor, R., Heenan, M., Coyle, S., Cleary, L, Kavanagh, K., Verhaegen, S., O'Loughlin, C., NicAmhlaoibh, R. and Clynes, M. (1998) 'Enhancement of chemotherapeutic drug toxicity to human tumour cells in vitro.by a subset of Non-Steroidal Anti-Inflammatory drugs (NSAIDs)'. European journal of Cancer, 34 :1250-1259. [Full-Text]
Book
Year
Publication
2011
Kavanagh K. (2011) Fungi: Biology and Applications.[DOI]
2007
Kavanagh K. (2007) Medical Mycology: Cellular and Molecular Techniques.[DOI]
2007
Kavanagh K. (2007) New insights in medical mycology.[DOI]
2005
Kavanagh K. (2005) Fungi: Biology and Applications.[DOI]
2006
Kavanagh, K. (2006) Medical Mycology: Cellular and Molecular Techniques. . : Wiley & Co. Ltd.
2001
Kavanagh K (2001) A Teachers Guide to Studying the Virulence factors of the Yeast Candida albicans. : Society for General Microbiology.
Conference Contribution
Year
Publication
2001
M. Brennan, G. Cotter (2001) British Society for Medical Mycology Imperial College, London, 04/01/2001-04/03/2001.
Article
Year
Publication
2012
Fallon J.; Kelly J.; Kavanagh K. (2012) Galleria mellonella as a model for fungal pathogenicity testing. [Article] [DOI][Full-Text]
Editorial
Year
Publication
2013
Browne, N; Kavanagh, K (2013) Developing the potential of using Galleria mellonella larvae as models for studying brain infection by Listeria monocytogenes. AUSTIN: [Editorial] [DOI]
Aneja, B; Alam, S; Azam, M; Perwez, A; Haque, R; Rizvi, M; Maguire, R; Kavanagh, K; Yadava, U; Daniliuc, C; Azam, A; Mohammad, A (2017) Design and synthesis of small molecule inhibitors bearing 1,2,3-triazole/sulfonate pharmacophore from natural precursors for the treatment of bacterial infections. WASHINGTON: [Magazine Article]
2017
Montagner, D; Erxleben, A; Miguel, PS; Kavanagh, K; Kellett, A (2017) Estrogens-functionalized metal complexes: selective anticancer and antibacterial activity. NEW YORK: [Magazine Article] [Full-Text]
2017
Mohammad, A; Hasan, P; Pillalamarry, V; Irfan, M; Perwez, A; Ahmad, B; Yadava, U; Rizvi, M; Daniliuc, C; Maguire, R; Kavanagh, K; Addlagatta, A (2017) Diketo acids and their hybrid bioisoster derivatives as bacterial biofilm and Methionine Aminopeptidase (MetAP) inhibitors. WASHINGTON: [Magazine Article]
2015
McMahob, F; Gallagher, C; Clynes, M; O'Sullivan, F; Kavanagh, K (2015) Analysis of the role of Bacillus oleronius proteins in the induction of tissue damage and inflammation in ocular rosacea. NEW YORK: [Magazine Article]
2014
Maurer, E; Browne, N; Surlis, C; Kavanagh, K; Lass-Florl, C; Binder, U (2014) Galleria mellonella as a host model to study Aspergillus terreus virulence and amphotericin B resistance. HOBOKEN: [Magazine Article] [Full-Text]
2012
Coughlan, CA; Chotirmall, SH; Bergsson, G; Eshwika, A; Greene, CM; Gunaratnam, C; Kavanagh, K; Reeves, EP; McElvaney, NG (2012) Gliotoxin, the Aspergillus fumigatus virulence factor downregulates vitamin D receptor expression and initiates a T-helper 2 response in cystic fibrosis airway disease. HOBOKEN: [Magazine Article]
2011
Coughlan, CA; Reeves, EP; Bergsson, G; Greene, CM; Chotirmall, SH; Kavanagh, K; McElvaney, NG (2011) GLIOTOXIN SECRETION IS RESPONSIBLE FOR VITAMIN D RECEPTOR DOWN-REGULATION AND A HEIGHTENED T-HELPER 2 RESPONSE IN ASPERGILLUS FUMIGATUS COLONISED CYSTIC FIBROSIS AIRWAYS. MALDEN: [Magazine Article]
2010
Coughlan, C; Reeves, EP; Bergsson, G; Greene, C; Kavanagh, K; O'Neill, SJ; McElvaney, NG (2010) GLIOTOXIN, A SECONDARY METABOLITE OF ASPERGILLUS FUMIGATUS REGULATES VITAMIN D RECEPTOR EXPRESSION IN CYSTIC FIBROSIS. HOBOKEN: [Magazine Article] [Full-Text]
2008
Lacey, N; Kavanagh, K; Seltmann, H; Zouboulis, C; Powell, FC (2008) Antibiotics used in the treatment of rosacea affect proliferation and lipid production in SZ95 cells. MALDEN: [Magazine Article]
2005
Thati, B; Egan, DA; Kavanagh, K (2005) Induction of apoptosis by novel metal-based derivatives of coumarin. PHILADELPHIA: [Magazine Article]
1988
KAVANAGH, KA; WHITTAKER, PA (1988) THE EFFECT OF CELL RECYCLE BATCH FERMENTATION ON ETHANOL-PRODUCTION BY PACHYSOLEN-TANNOPHILUS AND CANDIDA-SHEHATAE. LONDON: [Magazine Article]
Reviews
Year
Publication
2018
Sheehan, G; Garvey, A; Croke, M; Kavanagh, K (2018) Innate humoral immune defences in mammals and insects: The same, with differences ?. PHILADELPHIA: [Reviews] [DOI][Full-Text]
2016
Margalit A.; Kowalczyk M.; Zaba R.; Kavanagh K. (2016) The role of altered cutaneous immune responses in the induction and persistence of rosacea. [Reviews] [DOI][Full-Text]
2015
Margalit, A; Kavanagh, K (2015) The innate immune response to Aspergillus fumigatus at the alveolar surface. OXFORD: [Reviews] [DOI][Full-Text]
2013
Browne, N; Heelan, M; Kavanagh, K (2013) An analysis of the structural and functional similarities of insect hemocytes and mammalian phagocytes. AUSTIN: [Reviews] [DOI][Full-Text]
2012
Jarmuda, S; O'Reilly, N; Zaba, R; Jakubowicz, O; Szkaradkiewicz, A; Kavanagh, K (2012) Potential role of Demodex mites and bacteria in the induction of rosacea. READING: [Reviews] [DOI][Full-Text]
2012
McCann, M; Kellett, A; Kavanagh, K; Devereux, M; Santos, ALS (2012) Deciphering the Antimicrobial Activity of Phenanthroline Chelators. SHARJAH: [Reviews]
2010
Kavanagh K.; Fallon J. (2010) Galleria mellonella larvae as models for studying fungal virulence. [Reviews] [DOI][Full-Text]
2007
Kavanagh K.; Reeves E. (2007) Insect and mammalian innate immune responses are much alike. [Reviews] [Full-Text]
2004
Kavanagh, K; Reeves, EP (2004) Exploiting the potential of insects for in vivo pathogenicity testing of microbial pathogens. AMSTERDAM: [Reviews] [DOI][Full-Text]
2004
Kavanagh, K; Dowd, S (2004) Histatins: antimicrobial peptides with therapeutic potential. LONDON: [Reviews] [DOI][Full-Text]
2001
Daly, P; Kavanagh, K (2001) Pulmonary aspergillosis: clinical presentation, diagnosis and therapy. LONDON: [Reviews] [Full-Text]
2000
Cotter, G; Kavanagh, K (2000) Adherence mechanisms of Candida albicans. LONDON: [Reviews] [Full-Text]
1999
Murphy, A; Kavanagh, K (1999) Emergence of Saccharomyces cerevisiae as a human pathogen Implications for biotechnology. NEW YORK: [Reviews] [Full-Text]
Thesis
Year
Publication
2013
Matthew O’Brien (2013) Molecular and epidemiological studies of Trichoderma aggressivum. NUIM: [Thesis]
2012
Smith, A. (2012) Synthesis and characterization of silver(I) bioglues and assessment of biological activity of AgNO3 against Staphylococcus aureus. NUIM: [Thesis]
2012
Banville, N (2012) A comparison of the innate immune responses of humans and insects. NUIM: [Thesis]
2012
Madigan, G. (2012) Evaluation of different methods for the detection of Mycobacterium bovis in lymph tissue. NUIM: [Thesis]
2012
O'Reilly, N. (2012) An analysis of the role of Bacillus oleronius in the induction of rosacea. NUIM: [Thesis]
2011
Gallagher, L (2011) Functional Genomic Analysis of Natural Product Biosynthesis and Secretion in Aspergillus fumigatus’. NUIM: [Thesis]
2011
Duff, B (2011) In vitro pharmacological and proteomic effects of novel metal-based anti-cancer agents. NUIM & ITT Dublin: [Thesis]
2011
Tomkins, K (2011) A Molecular and Proteomic Investigation of the in Vitro and In Vivo Anti-microbial Efficacy of Novel Silver(I)-Coumarin Compounds. NUIM & ITT Dublin: [Thesis]
2010
Piasecka, J. (2010) Molecular and microbiological methods for the detection and measurement of dry bubble caused by Lecanicillium fungicola on mushroom farms. NUIM: [Thesis]
2010
Fallon, J. (2010) An analysis of the interaction of environmental and clinical isolates of Aspergillus fumigatus with vertebrate and invertebrate immune responses. NUIM: [Thesis]
2008
Mowlds, P. (2008) An analysis of the cellular and humoral immune responses of Galleria mellonella to fungal pathogens. NUIM: [Thesis]
2008
Kelly, J. (2008) An examination of the interaction of caspofungin with the yeast Candida albicans.’. NUIM: [Thesis]
2007
Lacey, N. (2007) Role of Bacillus oleronius in the induction of papulopustular rosacea.”. NUIM: [Thesis]
2007
Rowan, R. (2007) Investigations into the anti-Candida albicans of Silver(I) containing drugs. NUIM: [Thesis]
2007
Corrigan, M. (2007) An investigation of the interaction of Amphotericin B with the human pathogenic yeast Candida albicans. [Thesis]
2006
Thati, B (2006) A study of mode of action of novel metal based drugs as antimicrobial and anti-neoplastic agents. NUIM & ITT Dublin: [Thesis]
2006
Renwick, J. (2006) Analysis of insect immune response to Aspergillus fumigatus. NUIM: [Thesis]
2005
Bergin, D. (2005) Analysis of insect immune responses to fungal infection. [Thesis]
2004
Neville, C. (2004) Identification and characterisation of NRP synthetase and 4’-Phosphopantetheinyl transferase genes within Aspergillus fumigatus”. NUIM: [Thesis]
2004
Delaney, S. (2004) An investigation of the role of bacterial and Demodex associated antigens in the induction of Rosacea. NUIM: [Thesis]
2004
Eshwika, A. (2004) Metal-based anti-microbial drugs: Synthesis, characterisation and biological testing. NUIM: [Thesis]
2004
Geraghty, P (2004) The role of the mitochondrion in fungal pathogenicity. NUIM: [Thesis]
2004
O'Keeffe, J. (2004) An investigation of the interaction of anti-neoplatic agents with yeast drug efflux pumps. NUIM: [Thesis]
2002
Maye, L. (2002) Elucidation of role of adhesins of Candida albicans. [Thesis]
2002
Connolly, M. (2002) A study of factors affecting mushroom (Agaricus bisporus) quality, their interaction and control. NUIM: [Thesis]
2002
Martin, J. (2002) High level expression and characterisation of phytases from genetically modified strains of Aspergillus. NUIM: [Thesis]
2001
Murphy, A. (2001) An investigation of the virulence factors of clinical isolates of Saccharomyces cerevisiae. NUI M: [Thesis]
2001
Brennan, M (2001) Development of an insect model for studying fungal pathogenicity. [Thesis]
2000
Al Rawi, N (2000) Characterisation of yeast implicated in vulvovaginal candidosis in Irish women. NUI: [Thesis]
1999
Cotter, G (1999) A study of the effects of anti-neoplastic agents on the virulence of Candida albicans. NUI: [Thesis]
1999
Daly, P (1999) A study of the interaction of Aspergillus fumigatus virulence factors with human cancer cell lines. NUI: [Thesis]