Prof John P. Lowry

    Chemistry, Human Health Institute

    Gaeilge agus fáilte

    Professor

    MAP Lodge
    5
    (01) 708 4639

    Biography

    • 2012-Present: Professor/Chair of Chemistry, Maynooth University
    • 2007-2012: Adjunct Professor of Pharmacology, School of Biomolecular and Biomedical Sciences, UCD
    • 2006-2012: Professor/Chair and Head of Chemistry, National University of Ireland, Maynooth
    • 2004-2006: Lecturer & Examiner in Pharmacology/Principal Investigator: School of Biomolecular and Biomedical Sciences (Dept. of Pharmacology), UCD
    • 1998-2004: Lecturer & Examiner in Chemistry, National University of Ireland, Maynooth
    • 1996-1998: European Commission Marie Curie Fellow, UCD & University of Oxford
    • 1994-1996: European Commission Marie Curie Fellow, University of Oxford
    • 1992-1994: Forbairt Post-Doctoral Research Associate, UCD.
    • 1988-1992: PhD, Chemistry, UCD
    • 1984-88: BSc (Honours) Chemistry, UCD

    Research Interests

    • Neurochemistry
    • Analytical Chemistry
    • Electrochemistry
    • Pharmacology
    • Behavioural Neuroscience
    • Sensors and Biosensors
    • Brain Microdialysis

    Book

    Year Publication
    2002 O'Connor W.T., O'Connor J.J., Lowry J.P. and O'Neill R.D. (2002) Journal of Neuroscience Methods. : Elsevier Science B.V.
    2001 (2001) Monitoring Molecules in Neuroscience. : Univeristy College Dublin Press.

    Book Chapter

    Year Publication
    2006 Bolger, F.B., Serra, P.A., Dalton, M., O’Neill, R.D., Fillenz, M. and Lowry, J.P. (2006) 'Real-time monitoring of brain extracellular lactate' In: Di Chiara, G., Carboni, E., Valentini, V., Acquas, E., Bassareo, V. and Cadoni, C(Eds.). Monitoring Molecules in Neuroscience. Cagliari : University of Cagliari Press.
    2006 O’Brien, K.B., Killoran, S.J., O’Neill, R.D. and Lowry, J.P. (2006) 'Development of a catalase-based biosensor for the detection of endogenous hydrogen peroxide in brain extracellular fluid' In: Di Chiara, G., Carboni, E., Valentini, V., Acquas, E., Bassareo, V. and Cadoni, C(Eds.). Monitoring Molecules in Neuroscience. Cagliari : University of Cagliari Press.
    2006 Kirwan, S.M., Rocchita, G., Lowry, J.P. and O’Neill, R.D. (2006) 'Designing a polymer/enzyme composite biosensor suitable for clinical monitoring of glutamate in brain ECF' In: Monitoring Molecules in Neuroscience. Cagliari : University of Cagliari Press.
    2006 Finnerty, N.J., Bolger, F.B. and Lowry, J.P. (2006) 'Development of a microelectrochemical sensor for monitoring brain nitric oxide in vivo' In: Di Chiara, G., Carboni, E., Valentini, V., Acquas, E., Bassareo, V. and Cadoni, C(Eds.). Monitoring Molecules in Neuroscience. Cagliari : University of Cagliari Press.
    2006 Rocchitta, G., McMahon, C.P. Serra, P.A., Kirwan, S.M., Bolger, F.B., Lowry, J.P. and O’Neill, R.D. (2006) 'Significant enhancement of glutamate biosensor sensitivity using a polycation-modified polymer/enzyme composite sensing layer' In: Di Chiara, G., Carboni, E., Valentini, V., Acquas, E., Bassareo, V. and Cadoni, C(Eds.). Monitoring Molecules in Neuroscience. Cagliari : University of Cagliari Press.
    2006 Sheridan E., Obrenovich, T.P. Tedeschi, G. and Lowry, J.P. (2006) 'Development of a biosensor for the in vivo detection of brain extracellular D-Aspartate' In: Di Chiara, G., Carboni, E., Valentini, V., Acquas, E., Bassareo, V. and Cadoni, C(Eds.). In Monitoring Molecules in Neuroscience. Cagliara, Italy : University of Cagliari Press.
    2006 Fillenz, M., McHugh, S.B. Lowry, J.P. Bannerman, D.M. and Rawlins, J.N.P. (2006) 'An oxygen electrode for monitoring behaviour in freely moving rats' In: Di Chiara, G., Carboni, E., Valentini, V., Acquas, E., Bassareo, V. and Cadoni, C(Eds.). Monitoring Molecules in Neuroscience. Cagliari : University of Cagliari Press.
    2005 Lowry, J.P. and O'Neill, R.D. (2005) 'Neuroanalytical Chemistry In Vivo Using Biosensors' In: Grimes CA and Dickey EC(Eds.). Encyclopedia of Sensors. California : American Scientific Publishers.
    2003 Bolger, F.B. and Lowry, J.P. (2003) 'An investigation of Pt electrodes for in vivo monitoring of brain oxygen' In: Kehr, J., Fuxe, K., Ungerstedt, U. and Svensson, T.H(Eds.). Monitoring Molecules in Neuroscience. Stockholm : Karolinska University Press.
    2003 Dalton, M. and Lowry, J.P. (2003) 'Utilisation of polystyrene as an immobilisation matrix in the construction of a lactate biosensor for real-time in vivo monitoring' In: Kehr, J., Fuxe, K., Ungerstedt, U. and Svensson, T.H(Eds.). Monitoring Molecules in Neuroscience. Stockholm : Karolinska University Press.
    2003 Jago, J.M. and Lowry, J.P. (2003) 'An investigation of TTF:TCNQ biosensors for in vivo monitoring under O2 compromised conditions' In: Kehr, J., Fuxe, K., Ungerstedt, U. and Svensson, T.H(Eds.). Monitoring Molecules in Neuroscience. Stockholm : Karolinska University Press.
    2003 Lowry, J.P. and Finn, T. (2003) 'A Microelectrochemical Sensor for Real-Time Monitoring of Regional Cerebral Blood Flow' In: Kehr, J., Fuxe, K., Ungerstedt, U. and Svensson, T.H(Eds.). Monitoring Molecules in Neuroscience. Stockholm : Karolinska University Press.
    2001 Dalton, M and Lowry, J.P. (2001) 'A polystyrene-based glucose biosensor for in vivo neurochemical analysis' In: O'Connor, W.T., Lowry, J.P., O'Connor, J.J. and O'Neill, R.D(Eds.). Monitoring Molecules in Nevroscience. Dublin : University Press, University College Dublin.
    2001 Lowry, J.P., Ryan, MR. and O'Neill, R.D. (2001) 'Interference in biosensor detection of brain glutamate in vivo: possible role of endogenous ECF hydrogen peroxide' In: O'Connor, W.T., Lowry, J.P., O'Connor, JJ. and O'Neill, R.D(Eds.). Monitoring Molecules in Neuroscience. Dublin : University Press, University College Dublin.
    2001 Dunne, S.O., Brown, P.O. and Lowry, J.P. (2001) 'Biosensors for in vivo monitoring: a comparison of the interference rejection characteristics of poly(o-phenylenediamine) and Nafion' In: O'Connor, W.T, Lowry, J.P., O'Connor, JJ. and O'Neill, R.D(Eds.). Monitoring Molecules in Neuroscience. Dublin : University Press, University College Dublin.
    2001 Fillenz, M., Lowry, J.P., Boutelle, M.G. and Miele, M. (2001) 'In vivo determination of activation-dependent metabolic coupling' In: Frackowiak, R.S.J., Magistretti, P.J., Shulman, R.G., Altman, J.S. and Adams, M(Eds.). Neuroenergetics: Relevance for functional brain imaging. Human Frontier Science Program, Workshop XI, Strasbourg; Vol. 11. Strasbourg : Human Frontier Science Programme.
    2001 Lowry, J.P. and Fillenz, M. (2001) 'Brain energy metabolism: an investigation using real-time amperometric sensors' In: O'Connor, W.T., Lowry, J.P., O'Connor, JJ. and O'Neill, R.D(Eds.). Monitoring Molecules in Neuroscience. Dublin : University Press, University College Dublin.
    2001 Dixon, B.M., Lowry, J.P. and O'Neill, R.D. (2001) 'Oxygen dependence of a enzyme/polymer biosensor designed for brain glucose detection in vivo' In: O'Connor, W.T., Lowry, J.P., O'Connor, J.J. and O'Neill, R.D(Eds.). Monitoring Molecules in Neuroscience. Dublin : University Press, University College Dublin.
    2000 O'Neill, R.D. and Lowry, J.P. (2000) 'Voltammetry In Vivo for Chemical Analysis of the Living Brain' In: R.A. Meyers(Eds.). Encyclopedia of Analytical Chemistry. Instrumentation and Applications. Chichester, UK : John Wiley and Sons.
    1999 Lowry, JJP., Harford, C. J., (JNeill, R.D. and Fillenz, M. (1999) 'Brain Ascorbic Acid: Influence of Voltammetric Technique on Recorded Signal' In: Rollema, H., Abercrombie, E., Sulzer, D., Zackheim, J(Eds.). Monitoring Molecules in Neuroscience. Newark : University Press, The State University of New Jersey.
    1999 Dixon, B.M., Ryan, M.R., Lowry, J.P. and O'Neill, R.D. (1999) 'A glutamate biosensor with high oxygen tolerance for neurochemical analysis in vivo' In: H. Rollema, E. Abercrombie, D. Sulzer and J. Zackheim(Eds.). Monitoring Molecules in Neuroscience. Newark : University Press, The State University of New Jersey.
    1999 Craig, J.D., Ryan, M.R., Lowry, J.P. and R.D. O'Neill. (1999) 'Permselective polymers in the design of biosensors for chemical analysis in vivo' In: H. Rollema, E. Abercrombie, D. Sulzer and J. Zackheim(Eds.). Monitoring Molecules in Neuroscience. Newark : University Press, The State University of New Jersey.
    1999 Dalton, M. and Lowry, J.P. (1999) 'Nafion-modified carbon paste biosensors for in vivo neurochemical analysis: the effect of surfactant' In: H. Rollema, E. Abercrombie, D. Sulzer and J. Zackheim(Eds.). Monitoring Molecules in Newoscience. Newark : University Press, The State University of New Jersey.
    1998 Lowry, J.P. and Fillenz, M. (1998) 'Determination of brain extracellular glucose in vivo with an implanted biosensor' In: Teelken, A. W. and Korf, J(Eds.). Neurochemistry. New York : Plenum Publishing Corporation.
    1996 Lowry, J.P. and Fillenz, M. (1996) 'Simultaneous real-time monitoring of glucose and oxygen in vivo' In: Monitoring Molecules in Neuroscience, Proceedings of the 7th International Conference on In Vivo Methods, University of La Laguna, Spain.
    1996 Ryan, M.R., Lowry, J.P. and O'Neill, R.D. (1996) 'Partial optimisation of a glutamate biosensor for neurochemical applications in vivo' In: González-Mora J.L., Borges R., Mas M(Eds.). Monitoring Molecules in Neuroscience, Proceedings of the 7th International Conference on In Vivo Methods, University of La Laguna, Spain.
    1996 Lowry, J.P., Boutelle, M.G., O'Neill, R.D. and Fillenz, M. (1996) 'A glucose biosensor: Real-time monitoring of extracellular glucose' In: González-Mora J.L., Borges R., Mas M(Eds.). Monitoring Molecules in Neuroscience, Proceedings of the 7th International Conference on In Vivo Methods, University of La Laguna, Spain.
    1994 Lowry, J.P. and O'Neill, R.D. (1994) 'Chronically implantable glucose electrode based on a polymer/enzyme composite' In: Louilot, A., Durkin, T., Spampinato, U., Cador, M(Eds.). Monitoring Molecules in Neuroscience, Proceedings of the 6th International Conference on In Vivo Methods, Universities of Bordeaux I and II, Bordeaux.
    1994 Duff, A., Lowry, J.P. and O'Neill, R.D. (1994) 'Uric acid levels as an index of brain tissue condition during in vivo monitoring experiments' In: Louilot, A., Durkin, T., Spampinato, U., Cador, M(Eds.). Monitoring Molecules in Neuroscience, Proceedings of the 6th International Conference on In Vivo Methods, Universities of Bordeaux I and II, Bordeaux.
    1991 Lowry, J.P. and O'Neill, R.D. (1991) 'Enhancement of the glucose to ascorbate response at glucose oxidase modified conducting organic salt electrodes' In: Rollema H., Westerink B., Drijfhout W.J(Eds.). Monitoring Molecules in Neuroscience: Proceedings of the 5th International Conference on In Vivo Methods, University Centre for Pharmacy, Gronigen.

    Peer Reviewed Journal

    Year Publication
    2014 Francois, J., Huxter, J., Conway, MW., Lowry, JP., Tricklebank, MD. and Gilmour, G. (2014) 'Differential Contributions of Infralimbic Prefrontal Cortex and Nucleus Accumbens during Reward-Based Learning and Extinction'. Neuroscience, 34 :596-607. [Full-Text]
    2013 Barkus C, Line SJ, Huber A, Capitao L, Lima J, Jennings K, Lowry J, Sharp T, Bannerman DM, McHugh SB. (2013) 'Variation in Serotonin Transporter Expression Modulates Fear-Evoked Hemodynamic Responses and Theta-Frequency Neuronal Oscillations in the Amygdala'. Biological Psychiatry, 1 :1-1. [Full-Text]
    2013 Finnerty, N.J., O'Riordan, S.L., Lowry, J.P., Cloutier, M., Wellstead, P. (2013) 'Continuous Real-Time in vivo Measurement of Cerebral Nitric Oxide Supports Theoretical Predictions of an Irreversible Switching in Cerebral ROS after Sufficient Exposure to External Toxins'. Parkinson's Disease, 3 :351-362. [Full-Text]
    2012 OConnor J.J. and Lowry J.P. (2012) 'A comparison of the effects of the dopamine partial agonists aripiprazole and (−)-3-PPP with quinpirole on stimulated dopamine release in the rat striatum: Studies using fast cyclic voltammetry in vitro'. European Journal of Pharmacology, 686 :60-65. [Full-Text]
    2011 Finnerty, N.J., O’Riordan, S.L., Brown, F.O., Serra, P.A., O’Neill, R.D. and Lowry, J.P. (2011) 'In vivo characterisation of a Nafion®-modified Pt electrode for real-time nitric oxide monitoring in brain extracellular fluid'. Analytical Methods, 4 :550-557. [DOI] [Full-Text]
    2010 McHugh, S.B., Fillenz, M., Lowry, J.P., Rawlins, N.P. and Bannerman, D.M. (2010) 'Brain tissue oxygen amperometry in behaving rats demonstrates functional dissociation of dorsal and ventral hippocampus during spatial processing and anxiety'. European Journal of Neuroscience, 33 :322-337. [Full-Text]
    2009 Brown, F.O., N.J. Finnerty and J.P. Lowry (2009) 'Nitric oxide monitoring in brain extracellular fluid: Characterisation of Nafion-modified Pt electrodes in vitro and in vivo'. Analysis, 134 :2012-2020. [Full-Text]
    2009 Al Mulla, I., J.P. Lowry, P.A. Serra, and R.D. O'Neill (2009) 'Development of a voltammetric technique for monitoring brain dopamine metabolism: compensation for interference caused by DOPAC electrogenerated during homovanillic acid detection'. The Analyst, 5 :893-898. [Full-Text]
    2009 Fejgin, K., E. Pålsson, C. Wass, N. Finnerty, J. Lowry and D. Klamer (2009) 'Prefrontal GABAB Receptor Activation Attenuates Phencyclidine-Induced Impairments of Prepulse Inhibition: Involvement of Nitric Oxide'. Neuropsychopharmacology, 34 :1673-1684. [Full-Text]
    2009 Bazzu, G., G. Puggioni, S. Dedola, G. Calia, G. Rocchitta, R. Migheli, M.S. Desole, J.P. Lowry, R.D. O'Neill, P. A. Serra (2009) 'Real-time monitoring of brain tissue oxygen using a miniaturized biotelemetric device implanted in freelymoving rats'. Journal of Analytical Chemistry, 81 :323-330. [Full-Text]
    2009 Sibson, N., McHugh, S., and Lowry, J.P. (2009) 'Combined fMRI and metabolic voltammetry in vivo: understanding the neurochemical basis of functional imaging signals'. Journal of Cerebral Blood Flow and Metabolism, 29 :S613-S614. [Full-Text]
    2009 Rothwell,S.A., M.E. Kinsella, Z.M. Zain, Pier A. Serra, G. Rocchitta, J.P. Lowry and R.D. O’Neill (2009) 'Contributions by a novel edge effect to thh permselectivity of an electrosynthesized polymer for microbiosensor applications'. Journal of Analytical Chemistry, :3911-3918. [Full-Text]
    2008 O'Neill, R.D., Lowry, J.P., Rocchitta, G. , McMahon, C.P. and Serra, P.A. (2008) 'Designing sensitive and selective polymer/enzyme composite biosensors for brain monitoring in vivo'. TrAC - Trends in Analytical Chemistry, 27 :78-88. [Full-Text]
    2007 McMahon, C.P., Rocchitta, G., Kirwan, S.M., Killoran, S.J., Serra, P.A. Lowry J.P. and O’Neill R.D. (2007) 'Oxygen tolerance of an implantable polymer/enzyme composite glutamate biosensor displaying polycation-enhanced substrate sensitivity'. 22 :1466-1473. [Full-Text]
    2007 Klamer, D.S., E.N. Palsson, C.E. Wass, K.W. Fejgin, N.J. Finnerty, J.P. Lowry, J.A. Engel and L.I. Svensson (2007) 'Animal models for the assessment of cognitive dysfunctions in schizophrenia: focus on the nitric oxide pathway'. European Neuropsychopharmacology, 17 :S188-S189.
    2007 Serra, P.A. Rocchitta, G., Bazzu, G., Manca, A., Puggioni, G.M., Lowry J.P. and O’Neill R.D. (2007) 'Design and construction of a low cost single-supply embedded telemetry system for amperometric biosensor applications'. Sensors and Actuators, B: Chemical, 122 :118-126. [Full-Text]
    2007 Kinsella, M.E., Lowry, J.P. and O'Neill, R.D. (2007) 'Biosensor for the neurotransmitter L-glutamic acid: Development and characterisation'. Journal of Neurochemistry, 102 (Suppl. 1) .
    2006 Lowry, J.P., Mc Mahon, C.P., Rocchitta, G., Serra, P., Kirwan, S.M. and O'Neill, R.D. (2006) 'The efficiency of immobilised glutamate oxidase decreases with surface enzyme loading: an electrostatic effect, and reversal by a polycation significantly enhances biosensor sensitivity'. The Analyst, 131 :68-72. [Full-Text]
    2006 McMahon, C.P., Rocchitta, G., Serra, P.A., Kirwan, S.M., Lowry, J.P. & O'Neill, R.D. (2006) 'Control of the oxygen dependence of an implantable polymer/enzyme composite biosensor for glutamate'. Journal of Analytical Chemistry, 78 :2352-2359. [Full-Text]
    2005 Brown, F.O., Finnerty, N.J., Bolger, F.B., Millar, J. and Lowry, J.P. (2005) 'Calibration of NO sensors for In Vivo Voltammetry: Laboratory synthesis of NO and the use of UV-visible spectroscopy in determining stock concentrations'. Analytical and Bioanalytical Chemistry, 381 :964-971. [Full-Text]
    2005 Bolger, F.B. and Lowry, J.P. (2005) 'Brain Tissue Oxygen: In Vivo Monitoring using Carbon Paste Electrodes'. Sensors, 5 :473-487. [Full-Text]
    2004 Lowry, J.P. (2004) 'Monitoring Real-time Metabolite Trafficking in the Brain using Microelectrochemical Biosensors'. ANNALS OF THE MARIE CURIE FELLOWSHIP ASSOCIATION, III :92-97. [Full-Text]
    2003 Brown, F.O. and Lowry, J.P. (2003) 'Microelectrochemical Sensors for In Vivo Brain Analysis: An Investigation of Procedures for Modifying Pt Electrodes Using Nafion®'. The Analyst, 128 :700-705. [Full-Text]
    2002 Dixon, B.M., Lowry, J.P. and O’Neill, R.D. (2002) 'Oxygen dependence of an enzyme/polymer biosensor for monitoring brain glucose in vivo'. Journal of Neuroscience Methods, 119 :135-142. [Full-Text]
    2002 O’Connor, W.T., O’Connor, J.J., Lowry, J.P. and O’Neill, R.D. (2002) 'In Vivo Methods: Monitoring Molecules in Neuroscience'. Journal of Neuroscience Methods, 119 :105-107. [Full-Text]
    2001 Lowry, J.P. and Fillenz, M. (2001) 'The role of astrocytes in neuronal metabolism: Real time monitoring of metabolic trafficking'. Journal of Neurochemistry, 78 (Suppl. 1) .
    2001 Lowry, J.P., Dunne, S.O. and Fillenz, M. (2001) 'In Vivo Evidence Supporting Compartmentalisation in Brain Energy Metabolism'. 170 :103-104.
    2001 Lowry, J.P. and Fillenz, M. (2001) 'Real-Time Monitoring of Brain Energy Metabolism In Vivo using Microelectrochemical Sensors: The Effects of Anesthesia'. Bioelectrochemistry, 54 :39-47. [Full-Text]
    1999 Fillenz, M., Lowry, J.P., Boutelle, M.G. and Fray, A.E. (1999) 'The role of astrocytes and noradrenaline in neuronal glucose metabolism'. Acta Physiologica Scandinavica, 167 :275-284. [Full-Text]
    1998 O'Neill, R.D., Lowry, J.P. and Mas, M. (1998) 'Monitoring brain chemistry in vivo: Voltammetric techniques, sensors and behavioral applications'. Critical Reviews in Neurobiology, 12 :69-127.
    1998 Lowry, J.P., Ryan, M.R. and O'Neill, R.D. (1998) 'Behaviourally induced changes in ectracellular levels of brain glutamate monitored at 1 s resolution with an implanted biosensor'. Analytical Communications, 35 :87-89. [Full-Text]
    1998 Lowry, J.P., CWeill, R.D., Boutelle, M.G. and Fillenz, M. (1998) 'Continuous monitoring of extracellular glucose concentrations in the striatum of freely moving rats with an implanted glucose biosensor'. Journal of Neurochemistry, 70 :391-396. [Full-Text]
    1998 Lowry, J.P., Miele, M., O'Neill, R.D., Boutelle, M.G. and Fillenz, M. (1998) 'An amperometric glucose-oxidase/poly(o-phenylenediamine) biosensor for monitoring brain extracellular glucose: In vivo characterization in the striatum of freely-moving rats'. Journal of Neuroscience Methods, 79 :65-74. [Full-Text]
    1998 Lowry, J.P. and Fillenz, M. (1998) 'The relation between local cerebral blood flow and extracellular glucose in rat striatum'. Experimental Physiology, 83 :233-238. [Full-Text]
    1998 Lowry, J.P., Demestre, M. and Fillenz, M. (1998) 'Relation between local cerebral blood flow and extracellular glucose concentration in rat striatum during mild hypoxia and hyperoxia'. Developmental Neuroscience, 20 :52-58.
    1998 Fillenz, M. and Lowry, J.P. (1998) 'Studies of the source of glucose in the extracellular compartment of the rat brain'. Developmental Neuroscience, 20 :365-368.
    1997 Lowry, J.P. and Fillenz, M. (1997) 'The source of extracellular brain glucose during neuronal activation: A biosensor study'. Journal of Neurochemistry, 69 (Suppl.) .
    1997 Fillenz, M. and Lowry, J.P. (1997) 'The effect of mild hypoxia and hyperoxia on local cerebral blood flow and brain extracellular glucose'. Journal of Neurochemistry, 69 (Suppl.) .
    1997 Fillenz, M. and Lowry, J.P. (1997) 'The source of extracellular brain glucose and its role in neuronal glycolysis'. Journal of Neurochemistry, 69 (Suppl.) .
    1997 Lowry, J.P. and Fillenz, M. (1997) 'The relation between local cerebral blood flow and extracellular glucose concentration in rat striatum'. Physiology, 499P . [Full-Text]
    1997 Lowry, J.P. and Fillenz, M. (1997) 'Evidence for uncoupling of oxygen and glucose utilisation during neuronal activation in rat striatum'. Physiology, 498 :497-501. [Full-Text]
    1997 Ryan, M.R., Lowry, J.P. and O'Neill, R.D. (1997) 'A biosensor for neurotransmitter L-glutamic acid designed for efficient use of L-glutamate oxidase and effective rejection of interference'. The Analyst, 112 :1419-1424. [Full-Text]
    1997 Lowry, J.P., Boutelle, M.G. and Fillenz, M. (1997) 'Measurement of brain tissue oxygen at a carbon paste electrode can serve as an index of increases in regional cerebral blood flow'. Journal of Neuroscience Methods, 71 :177-182. [Full-Text]
    1996 Lowry, J.P., Boutelle, M.G., O'Neill, R.D. and Fillenz, M. (1996) 'Characterisation of carbon paste electrodes in vitro for simultaneous amperometric measurement of changes in oxygen and ascorbic acid concentrations in vivo'. The Analyst, 121 :761-766.
    1996 Lowry, J.P. and Fillenz, M. (1996) 'In vivo glucose measurements in rat striatum with an implanted sensor'. Journal of Neurochemistry, 66 (Suppl.2) .
    1994 Lowry, J.P., McAteer, K., El Attash, S.S., Duff, A. and O'Neill, R.D. (1994) 'Characterization of glucose oxidase-modified poly(phenylenediamine)-coated electrodes in vitro and in vivo: Homogeneous interference by ascorbic acid in hydrogen peroxide detection'. Journal of Analytical Chemistry, 66 :1754-1761. [Full-Text]
    1994 Lowry, J.P., McAteer, K., El Attash, S.S. and O'Neill, R.D. (1994) 'Efficient glucose detection in anaerobic solutions using an enzyme-modified electrode designed to detect H2O2: Implications for biomedical applications'. Chemical Communications, 21 :2483-2484. [Full-Text]
    1993 Lowry, J.P. and O'Neill, R.D. (1993) 'Partial characterization in vitro of glucose oxidase-modified poly(phenylenediamine)-coated electrodes for neurochemical analysis in vivo'. Electroanalysis, 6 :369-379.
    1992 Lowry, J.P. and O'Neill, R.D. (1992) 'Homogeneous mechanism of ascorbic acid interference in hydrogen peroxide detection at enzyme-modified electrodes'. Journal of Analytical Chemistry, 64 :453-456.
    1992 Lowry, J.P. and O'Neill, R.D. (1992) 'Strategies for reducing ascorbate interference at glucose oxidase modified conducting organic salt electrodes'. Journal of Electroanalytical Chemistry and Interfacial Electrochemistry, 334 :183-194.
    1991 O'Neill, R.D., Gonzalez-Mora, J.L., Boutelle, M.G., Ormonde, D.E., Lowry, J.P., Duff, A., Fumero, B., Fillenz, M. and Mas, M. (1991) 'Anomalously high concentrations of striatal extracellular uric acid detected with chronically implanted probes: Implications for in vivo sampling techniques'. Journal of Neurochemistry, 57 :22-29.
    1989 Lowry, J.P. and O'Neill, R.D. (1989) 'Detection of brain extracellular uric acid - Dependance on probe size'. Journal of Neuroscience Methods, 29 .

    Conference Contribution

    Year Publication
    2016 Michelle M. Doran; John P. Lowry (2016) The Role of Oxidative Stress Manifestation in Parkinson's Disease Monitoring Molecules in Neuroscience:16th International Conference Gothenburg, Sweeden, 29/05/2016-02/06/2016.
    2016 Saidhbhe L. O'Riordan; John P. Lowry (2016) Real-time electrochemical monitoring of physiological biomarkers: methods to investigate disorders of the brain and evaluate muscle tissue viability Monitoring Molecules in Neuroscience:16th International Conference Gothenburg, Sweeden, 29/07/2017-02/06/2016.
    2014 Michelle M. Doran; John P. Lowry (2014) Development of a Biosensor for the In-Vivo Detection of Superoxide 14th International Conference on Oxidative Stress Reduction,Redox Homeostasis & Antioxidants Paris, France, 12/06/2014-13/06/2014.
    2009 Dr. Andrew Kellett (2009) Anti-Tumor Potential and Mechanistic Studies of New Copper (II) Complexes Dublin IT, Science and Engineering, Chemistry, .
    2009 Dr. Seán Doyle (2009) Proteome mining of Aspergillus fumigatus - smack at the interface of chemistry and genomics NUIM, Science and Engineering, Chemistry, .
    2009 Dr. Martyn Boutelle (2009) Electroanalytical Methods - Powerful tools to study the problem of brain injury in patients Imperial College London, Science and Engineering, Chemistry, .
    2009 Professor Carmel Breslin (2009) Conducting Polymers with Molecular Recognition Sites: Applications in Electrochemical Sensing NUIM, Science and Engineering, Chemistry, .
    2009 Professor Carmel Breslin (2009) Electroanalytical Methods coupled with Spectroscopy and Surface Analysis NUIM, Science and Engineering, Chemistry, .
    2009 Dr. Michael Lyons (2009) Redox and catalytic properties of carbon nanotube modified electrodes Trinity College Dublin, Science and Engineering, Chemistry, .
    2009 Dr. André Brodkorb (2009) From nano to macro food structures - the relevance of chemistry in food science Teagasc Moorepark Food Research Centre, Science and Engineering, Chemistry, .
    2009 Professor Philip Bartlett (2009) RSC Tilden Endowed Lecture: Using Electrochemical SERS to Discriminate Mutations in DNA University of Southampton, Science and Engineering, Chemistry, .
    2009 Dr. Isabel Rozas (2009) Versatile guanidinium-like compounds in medicinal chemistry Trinity College Dublin, Science and Engineering, Chemistry, .
    2009 Professor Edmond Magner (2009) Bioelectrochemistry and Biocatalysis in Nonaqueous media University of Limerick, Science and Engineering, Chemistry, .
    2009 Dr. Fintan Kelleher (2009) Flexibility in Organic and Medicinal Chemistry - Friend or Foe!! IT Tallaght, Science and Engineering, Chemistry, .
    2009 Dr. John O'Connor (2009) Real time measurement of dopamine and serotonin in brain tissue UCD, Science and Engineering, Chemistry, .
    2009 Professor Robert O'Neill (2009) Long-term Brain Dopamine Dynamics: Sensor Survival during continuous recording UCD, Science and Engineering, Chemistry, .
    2009 Professor Robert Forster (2009) Small electrodes big impact Dublin City University, Science and Engineering, Chemistry, .
    2009 Professor Donal O'Shea (2009) Combining Therapuetic Treatments with Fluorescence Imaging: A Theranostic Approach UCD, Science and Engineering, Chemistry, .
    2009 Dr. Mary Pryce (2009) Photoactive organometallic materials DCU, Science and Engineering, Chemistry, .
    2009 Professor John Lowry (2009) Introduction to Electrochemistry: electrodes, cells, techniques and much more NUIM, Science and Engineering, Chemistry, .
    2001 Lowry, J.P. and Fillenz, M. (2001) Monitoring Molecules in Neuroscience, 9th International Conference on In Vivo Methods University College Dublin, Ireland, 16/06/2001-19/06/2001.

    Book Review

    Year Publication
    1995 O'Neill, R.D. and Lowry, J.P. (1995) On the significance of brain extracellular uric acid detected with in-vivo monitoring techniques: A review. BREV

    Magazine Article

    Year Publication
    2009 Lowry, J.P. and Scanlan, J. (2009) Blue Box sensors: Ireland's newest pharmaceutical devices company. [Magazine Article] [Full-Text]

    Thesis

    Year Publication
    2003 Mark C. Parkin (2003) The development of Rapid On-Line Neurochemical Assays. Investigating the Chemical Basis of Brain Injury. King’s College, London: THES
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